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HS Code |
833593 |
| Product Name | 2-Chloro-1-Bromopropane |
| Cas Number | 1825-85-6 |
| Molecular Formula | C3H6BrCl |
| Molecular Weight | 157.44 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 102-104°C |
| Melting Point | -85°C |
| Density | 1.474 g/cm³ at 20°C |
| Refractive Index | 1.482-1.484 |
| Flash Point | 20°C (closed cup) |
| Solubility In Water | Insoluble |
| Smiles | CC(Br)CCl |
| Inchi | InChI=1S/C3H6BrCl/c1-3(4)2-5/h3H,2H2,1H3 |
| Pubchem Cid | 68362 |
| Un Number | 1992 |
As an accredited 2-Chloro-1-Bromopropane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2-Chloro-1-Bromopropane is supplied in a 100 mL amber glass bottle with a secure screw cap and safety labeling. |
| Shipping | 2-Chloro-1-Bromopropane is shipped as a hazardous material, typically in sealed, chemical-resistant containers to prevent leaks. It should be labeled as flammable and corrosive, with UN number 2344. Shipping requires compliance with regulations such as DOT, IATA, or IMDG, ensuring proper ventilation, temperature control, and secure handling throughout transit. |
| Storage | 2-Chloro-1-bromopropane should be stored in a tightly closed container, kept in a cool, dry, well-ventilated area away from sources of ignition, heat, and direct sunlight. Avoid storage with strong oxidizers, acids, or bases. The storage area should be clearly labeled and equipped to contain leaks or spills, and access should be restricted to trained personnel. |
Applications of 2-Chloro-1-Bromopropane in Industrial Manufacturing2-Chloro-1-Bromopropane serves as a pivotal alkylating agent and synthetic intermediate in fine chemical manufacturing. Downstream industries rely on its controlled reactivity and selectivity to achieve specific molecular transformations. The application sectors below illustrate how integrators deploy this material in real industrial workflows. 1. Active Pharmaceutical Ingredient (API) SynthesisPharmaceutical manufacturers utilize this compound as a key intermediate in the synthesis of certain APIs requiring a chloro- and bromo-propyl group. Its balanced reactivity promotes selective alkylation reactions under phase transfer or solvent reflux conditions. During multi-step synthesis for classes such as beta-blockers or anti-infectives, the compound enters in the early alkylation or halogen exchange stages, ensuring stable intermediates for downstream functionalization. Industry compliance standards
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2. Agrochemical Synthesis (Herbicide and Fungicide Intermediates)Major agrochemical formulators employ this raw material in the construction of bromo- and chloro-alkyl skeletons found in select herbicide and fungicide active molecules. The compound’s alkylating function is critical for introducing halogenated side chains, often under catalyzed coupling or substitution conditions, delivering high-yield intermediates suited for scale-up in protected-flow or jacketed-glass reactors. Industry compliance standards
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3. Fine Chemicals for Laboratory Reagents ProductionChemical laboratories and specialty reagent producers harness this material in the manufacture of analytical building blocks and derivatization agents, particularly for chromatographic standards and NMR reference compounds. It enters site-specific halogenation or SN2 pathways, yielding well-defined single-component products standardized for analytical performance. Industry compliance standards
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4. Intermediate for Flavors and Fragrance IngredientsSpecialty fragrance and flavor manufacturers use this compound as an intermediate for constructing halogenated aliphatic side chains that impart unique notes or volatility in aroma molecules. The process typically involves selective configuration control and low-odor route development, applying the compound for etherification, esterification, or base-initiated halogen exchange under food-safe controlled conditions. Industry compliance standards
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5. Building Block for Specialty Polymer SynthesisProducers of specialty polymers and high-performance plastics deploy this intermediate during the synthesis of halogenated monomers. These monomers feed into controlled copolymerization or graft polymer routes, typically improving flame resistance or altering mechanical flexibility in engineering resin matrices. Reactors apply the material by strict metered addition to control copolymer chain structure and achieved halogen content specification. Industry compliance standards
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Every day on the plant floor, we see 2-Chloro-1-Bromopropane packed up and shipped off to research labs and industrial sites. This isn’t some niche chemical you find gathering dust in storage. This is a backbone intermediate that leaves our reactors with tight quality controls. Our production team knows that small lapses in distillation can raise traces of dihalide impurities, spiking background reactions in downstream syntheses. So, seeing the compound judged piece by piece on GC and NMR is routine, not special treatment.
We call it 2-Chloro-1-Bromopropane. You’ll often hear it referenced by its CAS number, 109-70-6, among folks who order by the drum. Chemists who know their halogenated hydrocarbons spot it right away by its colorless appearance and distinctive, harsh odor. Day in and day out on our floor, it behaves true to form: low boiling, highly flammable, and reactive under the right conditions. Its molecular formula is C3H6BrCl. What stands out is the dual halogenation—chlorine and bromine on a propane backbone—which gives it a welcome place in many syntheses.
For us, this compound tells a story about versatility. Working with pharmaceutical companies, we’ve learned that 2-Chloro-1-Bromopropane can serve as a key intermediate for custom molecule assembly. Researchers value its reactivity, since the two halogens, bromine and chlorine, open up straightforward substitution routes. You’ll find our product transforming into intricate building blocks for APIs, especially where selective displacement is required to avoid unwanted positional isomers.
In our own experience, the solvent extraction industry pulls in significant quantities as well. It stands out as a non-aromatic alternative where certain metal ions demand halogenated solvents for routine laboratory partitioning and analytics. Over the years, orders from analytical labs working on organic phase separators have climbed. Some combine 2-Chloro-1-Bromopropane with others like 1-chloropropane or 1-bromopropane, yet they argue our dual-halogen product gives better density control for phase separation.
Colleagues in the agrochemical space leverage its structure to deliver tailored halides into pesticide and herbicide R&D. The intermediate status of our product lets formulators target more complex molecules with reliable selectivity and fewer byproducts. We see repeat buyers who value not just consistency, but also the clean, crisp conversion this compound provides in alkylation and substitution reactions.
Most days, questions pop up about our lot consistency. Customers often worry about halogen content, water traces, residual solvents, or isomer ratio—issues that can trouble both gram-scale chemists and bulk buyers. Our production uses fractional distillation, which we monitor with in-house GC and titration to confirm not just purity by percent, but also identity and stability over storage. Open drums flowing down our lines meet a minimum assay of 98%, with our common industrial batches hitting well over 99% purity.
We know corrosivity can eat through cheaper drums. So, packaging matters. Our standard is metal or HDPE, based on transit requirements, with internal linings chosen to avoid catalyzing unwanted side reactions during shipment or storage. You’re less likely to find acidic residue left from batch carryover because we keep strict washout schedules and document all drum rotations. These habits aren’t buzzwords—they’re rooted in customer complaints from years past, and they inform our present-day protocols.
Stability is one question, though real-world shelf stability depends on both the storage environment and container integrity. Storing 2-Chloro-1-Bromopropane away from direct sunlight and at moderate temperatures extends usability. No one wants polymerization or discoloration toward the end of an inventory cycle. Our technical sheets spell out these realities, and our field technicians answer tough storage questions directly, not with hand-waiving.
Some users ask, “Why not stick with 1-chloropropane or 1-bromopropane for lab-scale synthesis?” Years of hands-on runs convince us that direct substitution doesn’t always give the same results. With both chlorine and bromine attached, you gain control over regioselectivity in nucleophilic substitutions—offering two distinct leaving groups. In reactions like Grignard formation, bromine’s lability often jumps ahead, while the remaining chlorine withstands harsher conditions for stepwise functional group installation.
We’ve seen customers using only mono-halogenated propanes struggle with controlling overalkylation. 2-Chloro-1-Bromopropane helps limit side chain branching and delivers compact integration in longer syntheses, especially when selectivity trumps yield. In solvents, the density is higher than most monohalides, so phase separations run faster and cleaner in extraction protocols.
Purity isn’t just a number. Repeating batches with erratic byproduct levels can wreck reaction consistency. We give particular attention to the removal of 1,2-dihalopropane and related halide contaminants during fractional distillation since even minor levels can produce side reactions that reduce yield or introduce impurities into downstream products. Working next to reactors for years, production staff know that a precise balance between speed, temperature and vacuum is key. We document these adjustments in our batch records—not for show, but to teach new employees how minor tweaks alter outcomes. Reduced batch-to-batch variability is the real selling point, not just a certificate stapled to a drum.
At the early stages of scaling up, we ran into solvent losses and significant odor leakage—an issue for staff and nearby residents alike. Since then, our process crowd has experimented with updated condenser units and double-loop scrubbers. The point isn’t to chase zero-emission buzzwords but to actually dial back real-world exposure and keep our site neighbors off the complaint line. In response, we also tweaked handling protocols to limit operator exposure on open lines in tank transfer areas. Every solution stems from real complaints and genuine learning.
We recall one long-term pharmaceutical client who returned several drums due to trace halogen crossover from a prior run. The incident forced our team to design single-use liners and switch to validation batches between different product runs. Traceability runs deep here, and each production shift holds responsibility for lot integrity. Clean custom equipment isolates our 2-Chloro-1-Bromopropane from higher reactivity halides and precludes unwanted side reactions that even a few ppm of impurity can trigger in tight pharmaceutical syntheses.
A few years ago, heavy rainfall and unexpected humidity on site exposed problems with capping and water ingress. In those weeks, we saw a jump in hydrolysis products—reminding everyone that even tightly monitored processes can slip. After that season, all warehouse containers received secondary sealing, and air-drying protocols for empties became part of the routine. As a manufacturer, direct experience with errant batches and tough corrective action leaves a mark. It gives us empathy for buyers burned by cloudy or yellowing product arriving at their doors.
Clients working on specialty surfactants tell us they appreciate dual-halogen intermediates for introducing polar anchor groups in their saponification or etherification steps. They use 2-Chloro-1-Bromopropane to precisely tailor molecular structures for both industrial and household spray formulations. The clean backdrop of our product ensures fewer side detergents and less color formation in final formulations—a big deal for detergent blenders tracking batch consistency across seasons.
On the research side, we’ve had conversations with organometallic chemists over the years who respect the unique role this compound plays as an alkylating agent. Because both bromine and chlorine have predictable leaving group tendencies, teams designing catalyst-bound alkylations adopt it to map mechanistic pathways or control for sequential substitutions. They share back how upgrades in purity correlate to more reliable pathway clarities in NMR and kinetic experiments.
Some industrial users in dye and pigment synthesis rely on our product for introducing halogenated side chains, which shift absorbance spectra or contribute to better long-term stability in harsh end-use environments. We collaborate to adjust supply volumes for pilot trials, scaling up as their R&D proves out hypotheses. In conversations, we encounter feedback about limits—like volatility issues and storage losses—and use those pain points to refine our container spec and batch size offerings.
Being on the manufacturing side, we see both laboratory-scale and industrial challenges unfold in real time. Our technical support doesn’t offer canned responses or point buyers to offshore stockpiles. Instead, we follow every unusual odor complaint or color change back to source tanks, compare GC-FID spectra against historical lots, and—where warranted—pull in site managers for line-by-line failure analysis. In the end, the best product information emerges from repeated production runs, process tweaks when things go sideways, and conversations with long-haul clients.
Many procurement teams looking for sustainable partnerships value stability in both price and supply chain. We operate batch production, balancing just-in-time orders with buffer inventory for customers who can’t afford unplanned downtime. This approach helps avoid price hikes tied to commodity halide market swings or global shipping snags. It also gives buyers one point of contact for all delivery crises, from container delays to customs snags, rather than chasing faceless logistics departments.
Our customer service team works side by side with plant floor staff—people who blend, distill, and ship product. If our product ever falls short of the GC specs, we don’t just pull affected drums from inventory. Plant technical leads recalibrate parameters, share new control charts, and document both the root cause and process fix. No dilution, no relabeling—just transparency about what happened and a timeline for when pure material will be shipping again. Years of maintaining this continuity show buyers that the integrity of the process carries right through to their doorstep.
Unlike single-halogen propanes offered by others, our dual-halogen structure has real advantages in terms of downstream flexibility. Chemists get more than just a moderately reactive alkyl halide; instead, they can switch between two reactivity profiles. This means control in stepwise organic synthesis, with the added bonus of cleaner separation in analytical extraction procedures. Our layout of refinery, blending, and quality testing right on site also trims down lead times compared to middlemen or repackagers. We don’t broker. We build, analyze, and ship.
Direct feedback loop from end users led us to narrow acceptable impurity ranges far below general market practice. We pay attention to 1,2-dihalopropanes and tracewater, keeping each lot within customer-specified outlier limits, with public reporting on deviations. Over the years, requests for documentation required us to invest in electronic batch records and cloud-based traceability. If you have issues, our technologists can reach any information right away—pulling certificates, past GC reports, handling logs, and corrective actions taken for past lots.
Pricing comes up during nearly every initial meeting with a new client. Our scale gives us flexibility, so we’re competitive for both drum lots and full containers. We also absorb volatility better, as we secure raw halogen supplies from longstanding partners, rather than spot-buying in risky markets. Our buyers don’t get sudden surprises because we mirror production to order volumes, and we’re upfront about cost drivers—energy, feedstocks, and compliance. These aren’t abstractions; they track right down to every kilogram delivered.
Shipping hazardous materials like 2-Chloro-1-Bromopropane demands more than compliance checklists. From our dock, each container gets a visual check for residue and secure seal. We run drum rotation tally sheets to keep old stock from creeping back into the shipment queue. Customers receiving product know what to expect, down to odor, color clarity, and drum labeling, because we prevent relabeling and cross-packing, which can cause downstream confusion and error.
Over the years, we’ve partnered with professional hazmat transit teams to cut down on lost product incidents and environmental releases during shipping. We require feedback from transport partners and insist on incident reports—not just regulatory compliance. In a few cases, field issues like punctured containers led us to redesign drum labeling and triple-layer linings for sensitive overseas routes. In our shop, continual improvement isn’t a brochure promise; it is a practical, hands-on process to maintain safe handling for all involved.
We are also honest about risks. 2-Chloro-1-Bromopropane must be handled with care: avoid open flames, minimize inhalation, and store on stable shelving away from oxidizers. Years of working with users directly taught us that many accidents arise from improper decanting or container damage during transfer. Our response includes training modules and direct phone access to plant technical staff for unexpected questions on safe transfer or first response.
Over decades, the chemical industry has shifted from treating secondary products as afterthoughts to investing real time in incremental improvements. We take this outlook seriously. Progress means examining every bottle that leaves the shop—and investigating any claim of unwanted odor, color, or phase anomaly with as much diligence as we put into first runs. Our goal remains to offer not just a high-purity 2-Chloro-1-Bromopropane, but a predictable tool for the libraries and industries that rely on it to push boundaries.
We don’t chase theoretical purity or one-off milestones. Instead, our plant aims to find the everyday reliability that research chemists, formulation teams, and industrial engineers need to run complex syntheses, purifications, and product launches. Tight process control, customer responsiveness, and honesty in reporting aren’t just industry goals—they are proven approaches that separate manufacturing from speculative stock and unvetted resellers. If your project depends on halogenated intermediates that do exactly what’s expected, we strive to ensure that both our people and our product serve the long game.
To sum up, our 2-Chloro-1-Bromopropane comes from hands-on experience, hard-earned improvement, and direct accountability. That’s the benefit of buying factory-direct from a dedicated crew of chemical makers who still walk their lines, inspect their work, and keep the end user in mind with every batch.