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HS Code |
201048 |
| Cas Number | 598-72-1 |
| Molecular Formula | C3H5BrO2 |
| Molecular Weight | 152.98 g/mol |
| Iupac Name | 2-Bromopropanoic acid |
| Appearance | White to off-white solid |
| Melting Point | 49-51 °C |
| Boiling Point | 208 °C |
| Density | 1.7 g/cm3 |
| Solubility In Water | Soluble |
| Pka | 2.60 |
| Flash Point | 99 °C (210 °F) |
| Synonyms | α-Bromopropionic acid, DL-2-Bromopropionic acid |
As an accredited 2-Bromopropionic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2-Bromopropionic Acid is supplied in a sealed, amber glass bottle with a secure screw cap and hazard labeling. |
| Shipping | 2-Bromopropionic Acid is shipped in tightly sealed containers, typically made of glass or high-density polyethylene, to prevent leaks and contamination. It should be kept in a cool, well-ventilated area, away from incompatible materials. Shipping complies with regulations for hazardous materials, including proper labeling and packaging to ensure safe transport. |
| Storage | 2-Bromopropionic acid should be stored in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers and bases. Keep the container tightly closed and clearly labeled. Use corrosion-resistant storage materials. Proper safety measures, including secondary containment, are recommended to prevent leaks or spills. Avoid moisture to prevent decomposition and contamination. |
Applications of 2-Bromopropionic Acid in Industrial ManufacturingOur production of 2-Bromopropionic Acid supports several advanced industrial fields by enabling precise chemical modifications required in pharmaceuticals, agrochemicals, specialty materials, and more. The following application sections reflect real manufacturing uses and integration points, focusing on downstream value in each industrial segment. 1. Pharmaceutical Active Ingredient Synthesis2-Bromopropionic Acid serves as a high-purity intermediate in the synthesis of select chiral pharmaceutical actives and custom intermediates. Within API production, it is frequently used to introduce brominated functional groups in controlled settings, supporting the stereoselective construction of key molecular scaffolds. Its haloacid structure enables functional transformations via nucleophilic substitution, esterification, or amide coupling reactions according to cGMP routes. Manufacturers demand strict traceability, impurity profiling, and validation data for batch release. Industry compliance standards
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2. Agrochemical Intermediate Production2-Bromopropionic Acid is processed as a reactive intermediate in the manufacture of selective herbicides and specialty crop protection agents. The brominated α-position enhances the capability for further derivatization, allowing downstream synthesis of esters or amides with unique biological profiles. Quality assurance must meet national agrochemical laws, and batch records must ensure absence of prohibited contaminants. We supply consistent lots to formulators requiring reproducibility in pilot and commercial plant runs. Industry compliance standards
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3. Synthesis of Chiral Building Blocks for Fine ChemicalsThe halogen functionality and stereocenter in 2-Bromopropionic Acid enable its extensive use in producing chiral auxiliaries, advanced ligands, and optically active building blocks required for asymmetric catalysis. Fine chemical manufacturers require reproducible optical purity and consistent enantiomeric excess, necessitating close cooperation on specification and analytical method validation. The material's reactivity under both SN2 and ester hydrolysis conditions is central for downstream chirality transfer, particularly in multi-step custom syntheses. Industry compliance standards
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4. Functional Monomer and Oligomer ModificationIn polymer and resin R&D, 2-Bromopropionic Acid provides a modifiable halogen group that supports post-polymerization grafting and surface functionalization. Researchers and formulators leverage its reactivity to develop specialty polymers with tailored physical and chemical properties, such as enhanced hydrophilicity or controlled degradation rates. The acid must meet electronics and industrial material safety standards, and its purity profile directly affects copolymer characteristics and stability. Industry compliance standards
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5. Specialty Surfactant and Amphiphile SynthesisIndustrial surfactant producers use bromopropionic acid in the synthesis of custom amphiphiles, where the bromoalkyl moiety allows for subsequent substitution or quaternization to generate functional head groups. Processing demands strict control of molecular distribution and minimization of residual bromide, aligning with regulatory controls for applications in emulsion systems, detergents, and certain metalworking fluids. Documentation and batch sampling follow sector-specific requirements to safeguard downstream blending reproducibility. Industry compliance standards
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In the maze of specialty chemicals, 2-Bromopropionic Acid stands out for both its unique features and its sheer usefulness across a surprising range of industries. Around our factory, we refer to this material daily not just by its name, but by how it performs and supports real-world applications: Chemical model C3H5BrO2, CAS number 598-72-1. If you spend enough time in the lab or supervise batches on the line, you start to appreciate both the subtleties of its production and how much difference those details can make once it leaves our hands.
Anyone who has spent time producing alpha-halo carboxylic acids knows that consistency separates reliable suppliers from the rest of the pack. We’ve invested in stainless reactors, tightly managed purification protocols, and rigorous quality instrumentation to ensure that with every batch, you receive a colorless to faintly yellow liquid or crystalline solid, nearly odorless, that consistently sits between 97%–99% purity by GC. While industrial requirements keep pushing for tighter tolerances, we’ve matched every client’s demand for precise assay, minimizing residual bromide or trace acetone. Lowering these impurities isn’t just about laboratory pride—end users in pharmaceuticals, fine chemicals, and polymer synthesis notice the difference in downstream reactions and final yield.
Our 2-Bromopropionic Acid features a melting point range of 44–48°C and a boiling point near 200°C (decomposes). Moisture control remains a challenge for many, but we consistently deliver moisture levels below 0.1% to preserve product stability. In our facilities, skilled technicians keep a close watch on each production step, avoiding the common pitfalls that plague bulk lots—coloration, polymerization, or excessive hydrolysis.
There’s a good reason this acid ends up all over lab benches and manufacturing lines around the world. The key comes down to that highly reactive bromine in the alpha position. This single atom opens the door to a wealth of transformation routes: nucleophilic substitution, esterification, and even controlled free-radical generation. We see our 2-Bromopropionic Acid used most frequently as an alkylating agent, a building block for chiral auxiliaries, and the formation of pharmaceutical intermediates.
When our industrial partners talk about cost and performance, they always bring up efficiency in yield and selectivity. Unlike generic propionic acid, the bromo-substituent allows for precise stepwise elaboration, sometimes cutting entire synthetic sequences compared to older methods. Major pharma manufacturers often approach us with custom requests: they need ultra-low levels of trace metals, or specific stereoisomer compositions. For those working at the leading edge of peptide synthesis, our material offers cleaner conversions—even after scale-up—than alternative supply routes.
The acid's prominence doesn’t just stem from organic synthesis. Polymer researchers use it as a chain transfer agent and a means to incorporate functional groups into complex structures. Even niche players in agricultural chemistry rely on the bromo group’s reactivity for custom crop protection agents. We ship bulk containers to textile and dye formulators who depend on its consistent reaction rates, just as much as academic researchers needing only a few grams for mechanistic studies.
Some clients ask how 2-Bromopropionic Acid stands apart from similar halogenated acids, like 2-Chloropropionic Acid or 2-Iodopropionic Acid. The distinction often traces back to reactivity, cost, and downstream product purity. The bromo variant bridges that crucial middle ground: more reactive and versatile than the chloro form, but easier to handle and less expensive than its iodine counterpart, which tends to be less stable and more prone to side reactions.
On the other side, generic propionic acid simply does not provide the functional handle needed for complex molecule assembly. While acetyl bromide or other alkyl bromides share some similar properties, they rarely deliver the selectivity and control in carboxylic acid chemistry demanded in industrial settings. For anyone running multiphase syntheses, the clean substitution reactions of 2-Bromopropionic Acid minimize byproduct load and offer straighter routes toward high-value targets.
On our shop floor, quality starts long before the drums head onto the loading dock. We source precursors that trace directly back to audited vendors with a history of chemical reliability. All incoming materials undergo screening—using both in-house labs and outside auditors—so no lot sneaks by without documentation. Staff run the reactors and purification columns not only based on SOPs but with instincts honed by years of handling sensitive halogenated compounds.
We avoid batch variability by controlling every step. Each lot receives unique IDs for traceability, making recalls and troubleshooting simpler for clients. Quality control teams draw samples at critical stages—often catching potential off-spec batches before blending or neutralization. Our routine uses both HPLC and gas chromatography, so by the time you receive a shipment, every specification (purity, water content, color, and trace contaminants) is measured and documented. Our experience proves that real-world reproducibility beats simple purity numbers found on generic brochures.
As most downstream users look for more environmentally conscious practices, we’ve invested in solvent recovery and reduced-waste production cycles. Our wastewater treatment removes even trace halides before anything leaves site, exceeding both national and international chemical safety standards. In the rare case of a complaint, we work directly with your technical team for root-cause analysis—not just a quick replacement—since the ultimate goal is keeping your operations running smoothly.
Handling 2-Bromopropionic Acid means grappling with both its strengths and quirks. It’s fairly stable at room temperature, but absorbs water if left exposed. Years of practice tell us to fill under dry nitrogen and use moisture-tight barrels or high-density polyethylene drums to cut down on decomposition. We’ve moved away from glass containers for bulk handling to reduce breakage and contamination risk.
Our own warehouse teams avoid stacking more than two drums, and every container gets a near field tag for electronic tracking. For labs who need to transfer multiple times, we recommend working quickly and capping containers as soon as possible. Leaving it exposed even for an hour on a humid day can raise the water content and, in the worst cases, promote unwanted hydrolysis. Safety teams regularly refresh training around eye and skin contact, as well as spill containment. After hundreds of shipments, these protocols reduce workplace exposure without relying on excessive automation.
Over the last decade, we’ve watched 2-Bromopropionic Acid shift from small-scale specialty orders to robust, ton-scale contracts. Its reliability in asymmetric synthesis led contract manufacturers to expand their purchase orders each year. Some clients use the acid to develop new antitumor agents or tailor-fit monomers for high-end polymers. Because we work directly with R&D chemists, we adjust specifications—not just based on what’s lowest cost, but on fit for their synthetic targets.
In conversations with pharmaceutical process teams, feedback often points to ease of purification in their downstream steps, partly thanks to our attention to trace impurity control. Lower baseline halide levels mean easier work-up and less spending on extra purification. We’ve seen academic groups publish on new catalyst systems based on our material, often referencing its reliability and purity across multiple reaction conditions. When end users move from pilot to production scale, fewer surprises arise because they know exactly what each drum will deliver.
A material’s story doesn’t end at the loading dock. 2-Bromopropionic Acid, like other halogenated organics, draws keen attention from global regulators. Each region enforces its own limits for emissions, workplace exposure, and waste halides, so as a manufacturer, we've taken compliance out of the hands of end users. Our environmental and safety team pre-tests all outgoing shipments for compliance with evolving standards. Documentation accompanies every container, not just for legal coverage but to provide transparent assurance.
We run hazard communication refreshers with every large client, rather than relying solely on electronic material safety data. The goal has always been to prevent accidental releases—either in transit or on-site—so we work with logistics firms experienced in hazardous cargos. Because national requirements update often, our own team attends regulatory briefings and upgrades internal labeling whenever guidelines evolve. This real-world attention keeps shipments moving across borders, and limits the potential for operational delays.
Market shocks, like raw material shortages or new shipping restrictions, test any manufacturer’s resilience. During raw bromine shortages, our team explored secondary sourcing, always weighing quality risks. In past periods of price volatility, long-term relationships provided a buffer—clients who trusted our traceability often kept orders steady, even as brokers scrambled for spot swaps.
Logistics created another ongoing challenge. To avoid transport delays, especially during sudden regulatory crackdowns, our exports leverage both land and sea routes, with real-time tracking by third-party auditors. In some destinations, we pre-position inventory to minimize lead times. By keeping communication clear with clients and never over-promising batch volumes, we've avoided the worst of the pressure points that have tripped up less committed suppliers.
What surprises most of our new customers isn’t just the purity or technical grade of 2-Bromopropionic Acid. They mention speed, traceability, and hands-on technical answers from our chemists, who have handled thousands of kilos across a tangled web of synthesis projects. Over time, we’ve seen how product stewardship matters more than any marketing claim. Each drum represents years of accumulated learning—choices about purification, logistics planning, and hazard prevention that never show up on a standard data sheet.
Our team stands in direct conversation with buyers—not through layers of distributors—so feedback loops back into every production run. Clients with novel applications sometimes push us into unexplored territory, leading to pilot trials, on-site troubleshooting, and co-development of new process adjustments. Sharing technical learning with formulation scientists, environmental officers, and production engineers remains key.
Many clients want improved sustainability, so we supply environmental impact assessments with orders and continue efforts to lower the environmental footprint of our facilities. Steps like upgrading to energy-conserving reactors, solvent recycling, and investing in ultrafiltration have paid off both in community trust and direct savings.
Balancing technical rigor with real-world challenges sets seasoned chemical manufacturing apart. Our close experience with 2-Bromopropionic Acid has turned early hurdles—batch traceability, impurity control, moisture management, and regulatory compliance—into everyday practice. We constantly review both equipment and process to keep ahead of industry shifts.
As customers continue developing more complex molecules, we expect 2-Bromopropionic Acid to remain essential across pharmaceutical, polymer, and specialty chemical fields. By staying rooted in direct production experience and a commitment to open, fact-grounded communication, we help our partners move from concept to market—with fewer headaches and higher confidence, batch after batch.
