2,4-Pentanedione

    • Product Name: 2,4-Pentanedione
    • Alias: Acetylacetone
    • Einecs: 204-634-0
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    149949

    Cas Number 123-54-6
    Molecular Formula C5H8O2
    Molar Mass 100.12 g/mol
    Iupac Name Pentane-2,4-dione
    Synonyms Acetylacetone
    Appearance Colorless to pale yellow liquid
    Melting Point -23 °C
    Boiling Point 140-142 °C
    Density 0.975 g/cm³
    Solubility In Water Miscible
    Vapor Pressure 3.1 mmHg at 20 °C
    Flash Point 35 °C (closed cup)

    As an accredited 2,4-Pentanedione factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2,4-Pentanedione is packaged in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 2,4-Pentanedione (Acetylacetone) should be shipped in tightly sealed containers, protected from light, heat, and sources of ignition. It is classified as a flammable liquid (UN 2310), requiring labeling and packaging per applicable regulations. Ensure proper ventilation, avoid incompatible materials, and include safety documentation during transport. Handle with appropriate precautions.
    Storage 2,4-Pentanedione should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances such as oxidizers. It should be kept away from heat, sparks, and open flames. Store under an inert atmosphere, such as nitrogen, if possible, and protect from moisture. Ensure proper labeling and access to spill containment materials.
    Application of 2,4-Pentanedione

    Applications of 2,4-Pentanedione in Industrial Manufacturing

    2,4-Pentanedione serves as a specialized intermediate and chelating agent in various industrial sectors, each with distinct downstream processes and regulatory requirements. As a direct manufacturer, we focus on delivering consistent quality for applications that demand precise formulations and process integration. Below, we outline key application segments, covering necessary compliance standards, typical addition rates, process integration, and end product categories.

    1. Chelating Agent for Metal Catalyst Preparation in Polymerization

    In the catalyst production sector, 2,4-Pentanedione chelates transition metals like vanadium, titanium, and cobalt, enabling reproducible formation of metal-acetylacetonate complexes for use in polyolefin and polyester polymerization. Its role remains critical for maintaining catalyst stability and activity control under operational conditions. Process engineers rely on its consistent reactivity to meet the demands of high-throughput industrial synthesis.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for catalyst production
    • REACH Annex XVII restrictions for specialty intermediates
    • Chinese National Standard QC/T 2528 for polymer-grade chemicals
    • EU CLP Regulation (EC) No 1272/2008 for catalyst ingredient labeling

    Typical usage ratio

    • Usually 0.5–1.8 molar equivalents per mole of metal ion, adjusted for specific transition metal and catalytic system parameters

    Downstream process integration

    • Added during the metal salt dissolution or ligand exchange stage prior to complex crystallization and purification steps

    Final product types

    • Vanadyl acetylacetonate (V(acac)3) for PE/PP catalyst systems
    • Titanium acetylacetonate (Ti(acac)3) for copolymer manufacture
    • Cobalt acetylacetonate for superabsorbent polymer production

    2. Precursor in Agrochemical Active Ingredient Synthesis

    Agrochemical manufacturers utilize 2,4-Pentanedione as a critical building block in synthesizing heterocyclic compounds, notably pyrazole, isoxazole, and triazole derivatives that function as herbicides, fungicides, and insecticides. This precursor enables control over ring closure, substitution, and functionalization steps under high-throughput, GMP-guided batch conditions typical of modern agrochemical plants.

    Industry compliance standards

    • FAO/WHO specification requirements for active ingredient purity
    • EU REACH registration as an intermediate for plant protection products
    • US EPA 40 CFR Part 158 – Data Requirements for Pesticides
    • ISO 17025 for analytical validation during quality control

    Typical usage ratio

    • Ranges from 0.8–1.2 mol per mol of target heterocycle precursor, with final ratio fine-tuned to minimize byproduct formation

    Downstream process integration

    • Charged at the initial condensation or cyclization stage in reactor trains processing nitrile or hydrazine reactants, followed by extraction and refining

    Final product types

    • Triazole-class fungicides (e.g., tebuconazole, triadimefon)
    • Isoxazole-based herbicide intermediates
    • Custom pyrazole insecticidal actives

    3. Intermediate for Pharmaceutical API Synthesis

    Pharmaceutical manufacturers leverage the diketone structure as an essential intermediate in multistage syntheses, including the construction of heterocycles present in antibacterial, antiviral, and CNS APIs. The tightly controlled environment of pharmaceutical API plants necessitates high-purity material and reliable batch-to-batch consistency to comply with regulatory submissions and in-process controls.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP / EP monograph identity and impurity requirements (when applicable)
    • FDA 21 CFR Part 211 for finished pharmaceuticals
    • EU GMP Part II for intermediates

    Typical usage ratio

    • Typically from 1.0–1.5 equivalence per mol of pharmaceutical precursor substrate, depending on target heterocycle complexity and yield optimization trials

    Downstream process integration

    • Dosed during early-stage condensation, acylation, or ring-forming reactions, prior to purification and subsequent transformation to API core scaffolds

    Final product types

    • Quinolone antibiotic APIs
    • Central nervous system drug precursors
    • Antiviral intermediate compounds

    4. Additive for Industrial Coating Resin Modification

    Major resin manufacturers employ 2,4-Pentanedione as a modifying agent and crosslinker in alkyd, polyester, and urethane resin systems for industrial coatings. The diketone improves crosslink density and pigment dispersion properties, which supports formulation stability and film performance in marine, automotive, and protective coatings sectors. Precise dosing and monitoring guide its use within strict finished product specifications.

    Industry compliance standards

    • ASTM D16–21: Standard Terminology for Paint, Related Coatings, Materials, and Applications
    • ISO 12944-6 for anticorrosion paint systems
    • EU Directive 2004/42/EC on VOC content in paints and varnishes
    • REACH Annex XVII chemical restrictions applicable to formulation ingredients

    Typical usage ratio

    • General addition between 0.2–1.0% by total resin mass; chemists adjust within this range according to pigment load and resin backbone reactivity

    Downstream process integration

    • Added during the resin synthesis stage after polyol/acid condensation, or blended in post-polymer modification prior to paint dispersion and milling

    Final product types

    • High-performance alkyd and polyester coatings
    • Two-component polyurethane industrial paints
    • Anticorrosion and marine coatings

    5. Raw Material for Solvent and Ink Additive Production

    Specialty solvent and ink industries process 2,4-Pentanedione as a precursor for formulating metal chelating solvent blends, ink stabilizers, and viscosity modifiers. High-purity requirements and tight process control enable manufacturers to manage evaporation, wetting, and drying profiles tailored for demanding printing and coating line environments.

    Industry compliance standards

    • ISO 2834-1:2020 for ink technology and proofing methods
    • IEC 60464 for solvent-based insulating varnishes
    • EN 71-3 for chemical safety in printing inks (toys and packaging)
    • REACH SVHC notifications for ink and solvent ingredients

    Typical usage ratio

    • Formulators introduce 2,4-Pentanedione at 0.5–2.1% by total formulation weight, and fine-tune depending on ink pigment type and solvent matrix

    Downstream process integration

    • Blended into solvent bases during additive compounding or introduced at the pigment pre-dispersion phase of ink manufacturing

    Final product types

    • Gravure and flexographic printing inks
    • Industrial solvent blends for varnishes and coatings
    • Inkjet and specialty marking fluids

    6. Analytical Reagent for Metal Ion Detection

    Analytical laboratories and in-house QC departments in metallurgy, environmental, and mining sectors use 2,4-Pentanedione as a chelating reagent for preparing derivatives that enable precise detection and quantitation of metal ions by spectrophotometric and chromatographic methods. This application relies on the purity and consistent chelation performance delivered by our manufacturing process.

    Industry compliance standards

    • ISO/IEC 17025 for laboratory testing and calibration
    • EPA SW-846 (Method 7196A) for hexavalent chromium analysis
    • AOAC Official Methods of Analysis for trace metals
    • EN 1483 for water quality mercury determination

    Typical usage ratio

    • Usage varies from 1–100 mg/L in buffer solutions, selected according to detection method sensitivity and target metal ion concentration

    Downstream process integration

    • Added directly to aqueous samples or buffer media at the reagent preparation step before colorimetric or chromatographic metal analysis

    Final product types

    • Prepared laboratory test kits for Cr, Mn, or Fe
    • Ready-to-use analytical reagents for ICP and AAS methods
    • Bespoke spectrophotometric calibration solutions

    Free Quote

    Competitive 2,4-Pentanedione prices that fit your budget—flexible terms and customized quotes for every order.

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    Tel: +8615365186327

    Email: admin@ascent-chem.com

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    Certification & Compliance
    More Introduction

    2,4-Pentanedione: At the Core of Our Chemical Expertise

    What Sets 2,4-Pentanedione Apart

    Years of hands-on production and problem-solving have made us familiar with the unique role that 2,4-pentanedione, often known as acetylacetone, plays in the modern chemical industry. The two carbonyl groups at the 2 and 4 positions make this molecule more than a simple diketone — it’s a workhorse that delivers dependable results across various industrial scenes. Many customers approach us seeking a material to strengthen coordination compounds or support specialty synthesis, and they find this compound’s enol-keto tautomerism sets it apart. This balanced tautomeric character doesn’t occur as strongly in similar di-carbonyl structures, and for us in chemical manufacturing, such behavior is more than an academic curiosity. It shows up in day-to-day plant operations, especially during solvent recovery or purification steps, where true volatility and purity drive the entire production.

    Building Purity From the Ground Up

    Every batch of 2,4-pentanedione moving out of our reactors starts with a careful look at raw materials, strict process parameters, and constant hands-on oversight. Those who use it in medicinal chemistry, coatings, metalworking fluids, or agrochemicals value high consistency. In our work, we’ve found even subtle changes in water content or the presence of trace impurities can disrupt downstream reactions, leading to wasted material and downtime for customers. The grades we offer—whether for laboratories running analytical methods or large-scale industrial applications—show differences not just in purity percentages, but in moisture, acidity, and even practical, fine points like color and odor. Over time, close collaboration with downstream users has sharpened our own protocols. For paint and pigment-makers, water content below 0.05% becomes critical, and color below 30 APHA holds real-world importance. Certain pharmaceutical applications call for the tightest grade, where careful distillation and closed handling lines truly matter. The needs aren’t a marketing checklist—they come from years of field experience, customer audits, and our own learning, batch by batch.

    Practical Experiences in Solvent and Chelation Chemistry

    In our factory, operators experience firsthand how the compound performs not only as a reagent but also as a ligand in complexation. The ability of 2,4-pentanedione to form strong chelates with metals like aluminum, nickel, zinc, and iron has shaped countless production campaigns here. If you’ve ever spent a night troubleshooting stubborn catalyst poisoning or color bodies in specialty chemical runs, the right diketone can be a lifesaver. During metal extraction projects, the selectivity of this compound compared to simpler diketones or monoketones makes all the difference—nobody wants to reprocess or clean fouled tanks because an off-grade raw material led to an incomplete extraction. Other systems, such as 3,5-heptanedione, compete in the same category but don’t create the same stable chelates or present the handy volatility range that simplifies distillation and recycling. We’ve seen many cases where a small difference like this, invisible on paper, produces hours of additional labor on the floor, repair costs, and stress for everyone involved.

    Differences With Similar Compounds

    Real-life work with 2,4-pentanedione brings constant reminders of the differences with other diketones or simple ketones. Some manufacturers try to swap it for less expensive, single-carbonyl reagents. Those efforts rarely last: the unique coordination profile, odor threshold, and even how it handles in continuous distillation units put acetylacetone ahead for serious manufacturing work. Longer chain diketones, such as 2,5-hexanedione or 3,5-heptanedione, don’t offer the same low freezing points or volatility that simplify handling. With methyl ethyl ketone or diacetone alcohol, the difference extends beyond reactivity—persistent odors can impact a workspace, and when you’re standing on the production line hours each week, even small changes in smell, color, and evaporation rate echo through maintenance intervals and worker comfort. The control we can exercise over these technical nuances stems from years of dedicated process refinement rather than off-the-shelf buying.

    Supporting Key Applications Through Reliable Chemistry

    We’ve worked alongside companies developing metal-organic precursors for CVD (chemical vapor deposition) in electronics, designing stabilizers for PVC resin, and structuring dry-erase coatings for schools. In each setting, the need for stable raw material supply and repeatable performance comes back to the choices made at our facility. For instance, in high-purity glassmaking or chip fabrication, certain minor side reactions produce colored impurities that standard commercial grades cannot tolerate; we’ve invested in utility upgrades and real-time analytics that nip these problems early. Users in the agrochemical sector pay close attention to the compound’s ability to dissolve both organic and inorganic salts—fluctuations in pH or even a one-degree shift in distillation temperature make production work more complicated. Partners in the lubricant, adhesive, and polymer field keep telling us: reliability saves them money and time, much more than ambitious claims.

    Experience With Customization and Scale-Up

    Over dozens of years, not all challenges fit a simple purity or specification adjustment. Researchers sometimes propose different solvent contents or tailored coloring; sometimes an innovation requires a blended mix. We’ve designed flexible processes to address such scenarios—modular reactors, in-line filtration upgrades, fast access to analytical data—without sacrificing safety or throughput. If a global supply chain issue disrupts a feedstock, our technical teams quickly adjust sourcing and processing to keep essential projects moving. For customers scaling from the lab to pilot to plant, each transition phase brings new hurdles: a drum from a distributor can behave very differently from a 20-ton bulk tank, especially over long hauls or with temperature swings during logistics. Our familiarity with real storage and shipping headaches informs how we wrap, palletize, and stabilize this compound—reducing leakage, caking, or pressure build-up during transit. The difference shows in the return rate and in the reduced back-and-forth with receiving docks, leading to smoother handovers and fewer headaches for everyone.

    Safety and Environmental Considerations in the Real World

    Any manufacturer that spends time with 2,4-pentanedione recognizes its toxicity and volatility aren’t abstract risks. Ensuring robust containment and proper exhaust ventilation matters for worker health, but no less for odor management and community impact. Over the years, our process safety measures have evolved in response to tighter local regulations and real-world events. Vapor monitoring, operator training, and automation spare both people and neighbors from accidental releases or fume exposure. Customers who have had previous suppliers neglect environmental controls end up facing local complaints, regulatory investigations, or product recalls—costs often skipped over in early price calculations. By handling the manufacturing end responsibly, we help partners meet their own safety goals and avoid supply chain disruptions that can set entire projects back by weeks or more.

    Commitment to Continuous Improvement

    What separates a seasoned manufacturer from a speculative operator comes down to how each team reacts to surprises in process or market conditions. Through the evolution of our plant automation and investments in technical staff, we’ve gathered a database of process scenarios, from best-case through the rough patches. This experience shows up not just in high average yields but in the day-to-day adaptability when something doesn’t go as planned—a feed pump fails, utility outages hit, or shipment routes get disrupted. Bringing 2,4-pentanedione to market in these conditions requires more than specifications written in an office; it draws on deep process knowledge, practical planning, and genuine responsibility toward end-users. We’ve seen too many times that chasing only the lowest cost with blind commoditization leads to hidden problems, either in broken supply promises or off-spec product. What we’ve chosen instead is a reputation for transparency, accuracy, and willingness to listen; most of our improvements have come out of industry partnerships instead of isolated lab work.

    Upholding Quality Without Gimmicks

    Buzzwords and flash marketing have no place in daily chemical production. Customers who stake their own jobs on batch-to-batch consistency look beyond price wars and glossy technical sheets. The value of our 2,4-pentanedione comes through in the absence of unwanted byproducts, tightly held physical properties, and full traceability — from the time feedstock arrives at our gate to each outgoing shipment. We maintain full documentation trails, not because regulators ask, but because end-users and their quality departments rely on detailed information to solve problems. End markets as different as aerospace, electronics, and crop protection trust this level of openness, especially following industry incidents where spot shortages or off-quality material upended sourcing plans for months. Delivering dependable 2,4-pentanedione comes down to a collective understanding built between manufacturing, technical support, logistics, and customer partners. The bonds formed from years of troubleshooting and shared successes matter more than any claim in the marketplace.

    In-Plant Logistics and Troubleshooting

    No chemical leaves our site without facing real-world transportation and storage. Drums and ISO tanks packed with 2,4-pentanedione often sit in varying conditions before reaching blending facilities, research labs, or field use. From first-hand accounts, we know that excessive temperature swings can cause pressure build-up or condensation, challenging even secure fittings and drum seals. We’ve refined our packaging and filling procedures to address this—selecting the right gasket materials, pre-flushing containers to remove air and vapor, and providing shipment tips that are born out of everyday freight challenges, not just theory. A product that builds up static or sweats moisture before it even gets to its end-use turns into a reliability risk. Careful attention to these details not only saves rework and lost shipments, but creates better trust between us and our customers. After all, a lost batch can mean lost weeks and unexpected overtime for everyone in the chain.

    The Human Side of Manufacturing

    Teams in any factory know the ups and downs that come with large-scale chemical production. Weather events, utility interruptions, staff turnover — these are not abstract scenarios, they’re everyday realities. The people producing, monitoring, and moving 2,4-pentanedione from our plant aren’t just executing protocols — they’re exercising judgment and adapting to circumstances as they unfold. Many improvements, such as real-time temperature monitoring and proactive scheduling, stemmed from shift workers’ observations and suggestions, rather than top-down directives. The bench chemist flagging a potential impurity or a logistics colleague finding a flaw in a loading procedure can drive big changes. This sense of shared responsibility infuses every campaign we run. Customers often remark that such grounded responsiveness is rare, and that’s why they stick with long-term suppliers who keep people at the center, not just systems.

    Looking Ahead While Honoring Lessons Learned

    Markets, regulations, and use cases for 2,4-pentanedione keep evolving. Regulatory agencies update listings, some end uses move toward greener chemistry, and customer audits grow more thorough each year. Having weathered supply chain disruptions, plant upgrades, and shifts in demand, our strategy combines readiness to pivot with stubborn dedication to the product’s fundamentals. We keep investing in process refinement, waste minimization, and emission controls, not for compliance alone, but to safeguard long-term performance and sustainability. Emerging applications—such as newer resist chemistries for photolithography or niche catalyst systems—demand smaller runs, quicker scale-ups, and tighter feedback. Our experience lets us support such shifts without losing sight of established customers’ needs. This balance grows out of trust, accumulated expertise, and honest dealings over years, not weeks.

    Final Thoughts From the Factory Floor

    2,4-pentanedione isn’t just another commodity on a flowchart—anyone who has spent shifts in a plant, run pilot batches, or delivered urgent loads during peak demand knows the difference that dedicated manufacturing makes. Industrial chemistry runs on reliability, personal integrity, and a willingness to confront challenges as they arise. The confidence that our product delivers, validated in day-to-day reality across numerous industries, stems not from paperwork or promotions, but from the collective effort of everyone at the plant. This approach isn’t the easiest path, but over the long haul, it produces results that partners truly value. For those who need more than just a chemical — for those who depend on it as a critical building block in their projects — that reliability and dedication mean the world.

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