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HS Code |
428126 |
| Cas Number | 615-50-9 |
| Molecular Formula | C7H10N2·H2SO4 |
| Molar Mass | 238.27 g/mol |
| Appearance | Gray to brown solid |
| Solubility In Water | Soluble |
| Melting Point | 174-178°C |
| Odor | Amine-like |
| Uses | Intermediate in dyes and pigments |
| Synonyms | Toluenediamine sulfate; Toluene-2,4-diamine sulfate |
| Stability | Stable under normal conditions |
| Storage Conditions | Store in a tightly closed container, away from light and moisture |
| Hazard Statements | May cause skin and eye irritation |
As an accredited 2,4-Diaminotoluene Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging consists of a 500g amber glass bottle, tightly sealed, labeled with hazard warnings and product details for 2,4-Diaminotoluene Sulfate. |
| Shipping | 2,4-Diaminotoluene Sulfate should be shipped in tightly sealed containers, kept dry, and protected from light and incompatible materials. It must be transported under regulatory guidelines for hazardous chemicals, typically labeled as harmful and irritant. Use appropriate cushioning and secondary containment to prevent leaks during transit, and ensure access to Safety Data Sheets. |
| Storage | 2,4-Diaminotoluene Sulfate should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers and acids. Protect it from moisture and direct sunlight. Ensure containers are clearly labeled and handled using proper personal protective equipment to avoid contact and inhalation. Keep out of reach of unauthorized personnel. |
Applications of 2,4-Diaminotoluene Sulfate in Industrial ManufacturingAs a direct manufacturer, we supply 2,4-diaminotoluene sulfate primarily to established industrial sectors that demand stable quality, controlled impurity levels, and reliable supply for scale-up processes. Our expertise supports clients in downstream formulation, process engineering, and regulatory compliance throughout all key application scenarios. 1. Colorant Intermediates for Hair Dye ManufacturingCommercial hair colorant producers incorporate 2,4-diaminotoluene sulfate as a primary intermediate in the synthesis of permanent oxidative dyes. Its amine functional groups enable precise coupling reactions with other color precursors under alkaline activation. European and North American formula developers have adopted it to achieve stable, reproducible color shades with effective penetration and minimal irritancy under approved conditions. Manufacturers focus on rigorous impurity control and batch traceability to ensure safe end-use on consumer hair. Industry compliance standards
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2. High-Performance Pigment and Organic Colorant SynthesisIndustrial pigment manufacturers use this raw material for synthesizing complex aromatic azo dyes and high-clarity organic pigments. It serves as a critical diamine source for diazotization and coupling reactions, resulting in yellow and brown pigment grades for plastics, inks, and paints. The material’s purity and particle size specification support demanding dispersibility and tint strength requirements in solvent- and water-based pigment manufacture. Industry compliance standards
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3. Polymerization Catalysts in Polyurethane Elastomer SystemsManufacturers of specialty polyurethane elastomers use controlled quantities of this compound as a chain modifier and curing accelerator. Its diamine structure allows selective reactivity with diisocyanates, leading to improved network uniformity, faster cure rates, and defined flexibility/hardness balances in final elastomeric parts. Raw material quality impacts reaction control and the physical properties of cast elastomer and microcellular foam production lines. Industry compliance standards
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4. Intermediate for Pharmaceutical Active Compound SynthesisAPI producers use 2,4-diaminotoluene sulfate as a registered intermediate in several multi-step syntheses of active pharmaceutical ingredients, particularly in the production of antihypertensives and contrast agents. Purity profile, trace residue limits, and lot reproducibility are strictly controlled as per cGMP principles. Documentation, change control, and full traceability are critical for global regulatory submission and product release. Industry compliance standards
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5. Curing Agent Precursor in Epoxy Resin SystemsIn advanced composites and coatings markets, resin formulators apply this compound as a precursor and modifier for aromatic polyamine epoxy curing agents. Proper selection of batch, particle size, and by-product control enables controlled reactivity for high glass transition temperature (Tg) applications. This results in enhanced thermal and mechanical performance meeting targeted aerospace, automotive, and electronics process requirements. Manufacturers maintain continuous monitoring of all critical quality attributes during blending and compounding. Industry compliance standards
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Over the years, our teams have handled long production runs of aromatic amines. Among them, 2,4-diaminotoluene sulfate stands out both for its particular chemistry and for the work it brings to the shop. Anyone spending enough time in chemical manufacturing comes to recognize the substances that keep you honest—where batch quality, purity, and consistency demand constant vigilance. 2,4-diaminotoluene sulfate asks for that and then some, starting with raw material sourcing and ending at the drum.
We supply this specialty compound in the form of a light brown to beige crystalline powder. Granule distribution, absence of caking, and a reliable settling profile seem ordinary on paper, but process changes reveal how small variances impact customer applications. Careful observation tells us a narrow melting range—usually between 173–177°C—signals very few residuals and tight control of synthesis conditions. Sulfate salts often defend their shelf life better in humid climates, sparing downstream formulators unnecessary headaches. Over time, robust packaging and attention to moisture uptake take priority.
Labels like “technical grade” or “high purity” do not say much about the real product unless you back them with evidence. We regularly produce two specification models: one suited to classic dye intermediates and a second for more demanding applications, such as specialty polymer additives. Customers look for main assay values exceeding 98 percent, but tolerances for ash, heavy metals, and insolubles speak volumes about the practicality and reliability of a supplier. Retaining trace element data in internal quality logs has become standard practice, especially since a single high-manganese batch in 2014 triggered a wave of customer technical calls. Transparency here improves trust and saves time.
The underlying chemistry around this product ties closely to classic aromatic amine production—still relevant after so many decades. We start with nitration of toluene under controlled acidic conditions to obtain dinitrotoluene. The challenge lands in reduction: maintaining a clean conversion prior to isolation of the sulfate salt form. Over-reduction leads to more undesired amines; under-reduction, to persistent nitro groups. Using sulfates rather than free bases gives improved handling, both for shipping and for the safety of those on the factory floor. Workers routinely feedback on dusting during bagging, so we choose flow aids based on real storage history and not just theoretical compatibility.
Decades of collaboration with end users have painted a clear picture. Hair dyes and permanent textile colors account for the largest share of demand. The oxidative color-forming process relies heavily on amines like this sulfate form to generate rich shades of brown, black, and blue. We have traced process complaints back to shifts in pH, water quality, or even dye-pot material, but the chemical’s behavior remains consistent as long as it stays dry and pure. In smaller volumes, the compound finds its way into adhesive and epoxy cure systems, creating flexible bonds that resist chemical drift over time.
Regulations evolve, meaning that the permitted use of aromatic diamines changes depending on geography and intended application. Years ago, certain formulations were dropped in Europe due to REACH rules, prompting customers in Asia and South America to search for alternative grades, or for substitutes with similar reactivity but improved toxicity profiles. Maintaining open conversations around compliance helps avoid confusion and supports safe innovation—both at the lab bench and in high-throughput colorant bottling.
Some customers compare 2,4-diaminotoluene sulfate to closely related products like the 2,6-isomer, or to para-phenylenediamine sulfate (PPD sulfate). Though the molecules look similar, small changes in substitution can lead to meaningful shifts in hue, dispersibility, and reaction rate. We once saw a batch intended for a blue-black dye run turn dull once 2,6-isomer was substituted due to a supply chain hiccup. That pain motivates our lab technicians to keep isomeric purity high and to communicate any blend changes up front.
The difference between using sulfate salts and their corresponding free bases often boils down to safety and operational smoothness. Sulfate forms resist oxidation and are much less prone to air-activated discoloration, especially in regions with long transit times or warehouse storage. From our standpoint, it helps that the sulfate salt leaves less amine odor during worker exposure and shipment. End users prefer the extra stability since it cuts down color-bleed issues and improves batch-to-batch consistency in finished products.
After investing in better containment systems and off-gas treatment, the repeatability and output of our sulfate production lines improved dramatically. We run quality checks not just at the end, but throughout key temperature plateaus and pressure stages. Failed batches no longer travel down the line, and upstream adjustments prevent downstream shame. Every sampling window adds another chance to intercept off-spec material before it becomes a costly return.
Older process protocols did not always include real-time elemental analysis. Modern requirements made this unavoidable. Our team introduced near-infrared and UV-vis spectrographs in-line so that impurity spikes appear live, long before packaging. These investments extend to granulation too. Low-dusting lots not only protect our staff, but also help customers avoid inconsistencies when weighing into small batch reactors.
Handling aromatic amines always draws health and safety concerns. 2,4-diaminotoluene sulfate, though more stable than some free-amine competitors, still demands respect. On the manufacturing floor, we enforce closed-system transfers and high-efficiency air handling. Inspection teams regularly check PPE stocks and waste collection lines. In past years, site audits exposed high-wear valve seats as a weak spot—where trace leaks encouraged brown residue buildup and uncomfortable odors. Since then, regular equipment swaps and more robust gaskets reduced downtime and cut process complaints.
Wastewater is a recurring topic on any plant manager’s to-do list. Our effluent treatment uses a combination of advanced carbon beds and controlled oxidation to neutralize amine content before water discharge. Samples collected upstream and downstream reveal how critical these steps have become for regulatory compliance. The plant’s neighbors appreciate the reduced odor profile, and regulators base permit renewals on such results.
Long gone are the days where just hitting a typical assay result counted as success. Now, buyers ask about residual solvents, sources of all raw materials, and even the specifics of our energy use during synthesis. We receive requests for analysis showing nitrosamine absence, in line with recent health concerns across the dye and cosmetic sectors. This steers us toward new purification routes, even if those disrupt standard yield expectations. Customers pursuing eco-certifications need documentation faster than ever. Behind every certificate of analysis, hours go into validating each data point and responding to technical queries from compliance officers and product safety teams.
Legislative shifts in major markets control much of our production planning. Regulatory shifts in North America or Asia affect not only how we make 2,4-diaminotoluene sulfate but also which versions reach certain ports. Our compliance group keeps contact with external consultants, scanning changes in chemical registration and substance monitoring. Changes in requirements for heavy metal content led us to swap out certain metal catalysts or starter grades, cost notwithstanding. These changes rarely follow a smooth or predictable pattern.
Unexpected clumping in sulfate powder used to generate multiple headaches for both packaging staff and warehouse receivers. In response, our engineers modified moisture set points and tweaked granulation equipment. The implementation of specialty liners showed a noticeable decrease in returns related to agglomerated product. These feedback loops between operations, customer service, and R&D boost overall process reliability—both for us and for end users. For shipment over long distances, especially to tropical ports, increased desiccant use means less performance loss on arrival.
Another persistent concern involves off-color lots, especially in batches produced during seasonal humidity surges. Installing dedicated climate controls in storage areas paid off by reducing yellowing incidents, preserving the intended light beige appearance. Maintenance supervisors track temperature and airflow, reporting near-miss incidents to site management. The reality of running shifts when ambient temperatures can swing so widely keeps demand high for process adaptability, especially during peak run schedules.
Product return rates and customer complaints dropped once our technical team offered virtual training and troubleshooting for application specialists. Sometimes, the underlying issue in an end-user process stems from water chemistry or uncalibrated weighing rather than from the compound itself. Open forums that share lessons learned improve both our product outputs and the user experience. The cycle of feedback and innovation never reaches a true endpoint.
Recent conversations with procurement and R&D teams explain why buyers sometimes consider alternatives like 2,6-diaminotoluene, meta-phenylenediamine, or other amine salts. Each brings trade-offs—be it in achievable color spectra, ease of handling, or cost of regulatory approval. We test these substitutes side-by-side to validate claims from literature against real production runs. Only in a handful of cases does another amine match the sulfate for oxidative color range and storage stability, especially under hot and humid transport. Our historical data supports continued investment in the sulfate’s specific production pathway rather than drifting too far toward speculative new raw materials.
Some users prioritize cost savings and attempt to downgrade to free base forms. This approach often stumbles—not just because of packaging and shelf-life, but also because of unpredictable color drift and increased sensitivity to ambient air. Consistent usage experience and clear visual cues keep users loyal to the sulfate salt over other alternatives, particularly in the tightly regulated world of hair and textile dyes.
Manufacturers like us gain unique insight by staying connected from synthesis bench to shipping dock. Each improvement in production or safety protocol comes directly from challenges faced on the floor or in customer facilities. The urge to find short-term shortcuts never pays off in this space—trace impurity readings and end-user concerns always catch up. A focus on real-time optimization, transparency, and consistent communication builds a supply chain that supports both bulk orders and high-purity specialty needs. This keeps 2,4-diaminotoluene sulfate ready to meet the evolving challenges industries bring to our door, today and tomorrow.