Products

2,4,6-Trichlorophenol

    • Product Name: 2,4,6-Trichlorophenol
    • Alias: Dowicide 2s
    • Einecs: 202-384-8
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    608552

    Chemical Name 2,4,6-Trichlorophenol
    Cas Number 88-06-2
    Molecular Formula C6H3Cl3O
    Molecular Weight 197.45 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 69-71 °C
    Boiling Point 246 °C
    Density 1.489 g/cm³
    Solubility In Water 0.08 g/100 mL (20 °C)
    Flash Point 132 °C
    Odor Phenolic, medicinal
    Pka 6.0
    Vapor Pressure 0.012 mmHg (25 °C)

    As an accredited 2,4,6-Trichlorophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle with a tight-sealed cap, labeled "2,4,6-Trichlorophenol," hazard symbols, and safety instructions.
    Shipping 2,4,6-Trichlorophenol is shipped as a hazardous material due to its toxic and corrosive properties. It must be packed in tightly sealed, chemical-resistant containers, clearly labeled with hazard warnings. Transport should comply with local and international regulations, such as DOT, IATA, or IMDG, to ensure safe handling and environmental protection.
    Storage 2,4,6-Trichlorophenol should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers and bases. Avoid exposure to light, heat, and moisture. The storage area should be clearly labeled, resistant to corrosion, and equipped with spill containment and emergency wash facilities. Handle under a fume hood to minimize inhalation risks.
    Application of 2,4,6-Trichlorophenol

    Applications of 2,4,6-Trichlorophenol in Industrial Manufacturing

    2,4,6-Trichlorophenol is a key intermediate in a variety of specialized industrial sectors. As an integrated chemical raw material producer, we supply this product in multiple purities and grades for controlled, critical use in regulated downstream manufacturing processes. The following application scenarios showcase how leading producers in dedicated markets incorporate this material for precise industrial synthesis, downstream formulation, and targeted product functionality.

    1. Intermediate for Pharmaceutical Synthesis (e.g. Antiseptics & Disinfectants)

    Many manufacturers utilize 2,4,6-Trichlorophenol during the synthesis of antiseptic agents such as hexachlorophene and other functional chlorinated biochemical derivatives. This compound reacts in controlled environments, often as a halogenation substrate or precursor, requiring strict attention to reaction temperature, acidity, and solvent system to ensure consistent conversion while meeting pharmacopeia purity demands for trace impurities and residual solvents. The processed intermediates undergo downstream formulation into disinfectant active ingredients for hospital and clinical use, where precise dosage control and impurity thresholds are critical for compliance and end-use safety.

    Industry compliance standards

    • USP, Ph.Eur. standards for hexachlorophene and related actives
    • 21 CFR Part 211 Current Good Manufacturing Practice (CGMP) for finished pharmaceuticals
    • ICH Q3A/B for impurity and residual solvent controls
    • REACH Annex XVII restrictions for trichlorophenol handling

    Typical usage ratio

    • Operation-dependent; commonly 80–95% conversion efficiency relative to target disinfectant intermediate
    • Reagent molar ratios adjusted based on desired chlorination or coupling, validated by pilot-scale batch testing

    Downstream process integration

    • Charger in halogenation or Mannich reaction reactors
    • Purification via distillation or crystallization before next synthesis stage
    • Vacuum drying and QC sample retention prior to API-grade conversion

    Final product types

    • Hexachlorophene bulk active ingredient
    • Specialty antiseptic agents for topical pharmaceuticals
    • Hospital-grade disinfectant formulations

    2. Synthesis of Wood Preservatives

    Specialty manufacturers in the wood protection sector apply 2,4,6-Trichlorophenol in formulating chlorinated phenol-based preservatives. These products extend timber life by inhibiting fungal and bacterial degradation. The process typically involves controlled blending with co-biocides and carrier solvents, followed by pressure impregnation into wood or board substrates. The efficacy of the preservative relies on accurate control of phenolic activity, permitted only under registered biocidal product regulations and subject to environmental emissions monitoring.

    Industry compliance standards

    • Biocidal Products Regulation (EU) 528/2012 and relevant national authorizations
    • US EPA FIFRA registration for wood preservatives
    • ISO 21887 for field testing wood preservatives
    • OSHA 29 CFR 1910.1200 for workplace chemical handling

    Typical usage ratio

    • Between 1.5% and 4% (w/w) active ingredient in finished biocide, adjusted based on timber exposure risk and application thickness
    • Ratio of co-biocides varies according to fungal spectrum and penetration depth requirements

    Downstream process integration

    • Pre-mixing in agitated blending tanks with solvent carriers
    • Pressure impregnation units for application to lumber, plywood, or utility poles
    • Post-application drying or kiln curing for solvent removal

    Final product types

    • Industrial and structural wood preservatives
    • Treated railway ties and utility poles
    • Exterior construction boards with anti-fungal protection

    3. Manufacturing of Pesticide Active Ingredients

    2,4,6-Trichlorophenol plays a critical role in synthesizing several chlorinated phenol-derived pesticides, such as fungicides and herbicidal actives. This process involves tightly controlled chlorination and coupling reactions, with careful temperature and pressure regulation to ensure selectivity and minimal byproduct formation. The finished technical-grade active ingredients are subject to multiple purification steps before micronization and formulation into agricultural products, with manufacturing operations rigorously documented to meet national and international pesticide registration requirements.

    Industry compliance standards

    • FAO/WHO specifications for technical-grade pesticide actives
    • ISO 9001:2015 for quality management in pesticide production
    • OECD Good Laboratory Practice (GLP) for product analysis
    • National regulations such as EPA (USA) or GB/T 1601-2010 (China) for pesticides

    Typical usage ratio

    • Active input typically 70–85% conversion efficiency depending on targeted active molecule
    • Stoichiometry tailored per downstream coupling partner and catalyst system

    Downstream process integration

    • Bulk reaction vessels for precursor chlorination or alkylation
    • Phase separation and solvent stripping before final product isolation
    • Granulation or micronization ahead of product formulation

    Final product types

    • Fungicides for cereal and fruit protection
    • Selective herbicidal actives for crop management
    • Bioactive intermediates for further agrochemical synthesis

    4. Dye and Pigment Intermediate

    Fine chemical makers and pigment producers rely on 2,4,6-Trichlorophenol as a building block for synthesizing certain specialty dyes and chromophore intermediates, particularly in the production of diaryl or triaryl methane dyes. The process leverages the compound’s reactivity in condensation or coupling reactions with aromatic amines or other halogenated aromatics, requiring stringent monitoring of pH, temperature, and impurity profile to achieve color strength and migration resistance in the final dye. Accurate feedstock analysis and process validation ensure product integrity for demanding end-use in plastics coloration, textile dyeing, and inks.

    Industry compliance standards

    • EN 71-3 for safety of toys (color migration)
    • REACH SVHC declarations for pigments and dyes
    • DIN 53316 (color fastness of plastics)
    • ISO 105 methods for textile dye performance

    Typical usage ratio

    • Intermediary use at 5–20% of total dye batch, depending on chromophore complexity and desired shade
    • Yield efficiency and ratio adjustment based on pigment loading in downstream compounding

    Downstream process integration

    • Condensation and coupling reactors, charge at controlled rates
    • Post-reaction crystallization and filtration
    • Integration into masterbatch or pigment dispersion systems

    Final product types

    • Specialty dye intermediates
    • Pigments for plastics, inks, and coatings
    • Textile coloring agents for synthetic and natural fibers

    Free Quote

    Competitive 2,4,6-Trichlorophenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615365186327 or mail to admin@ascent-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: admin@ascent-chem.com

    Get Free Quote of Ascent Petrochem Holdings Co., Limited

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,4,6-Trichlorophenol: Our Approach to a Fundamental Intermediate

    Overview of 2,4,6-Trichlorophenol

    Producing 2,4,6-Trichlorophenol means thinking about chemistry from both a practical and an industrial point of view. Structurally, 2,4,6-Trichlorophenol falls among polychlorinated phenols, where three chlorine atoms attach to a phenol ring at the 2, 4, and 6 positions. This feature gives it a unique profile for reactivity and selectivity in chemical synthesis routes. In our plant, we have focused on this compound both for its value in downstream chemistry and for its critical role in the synthesis of more specialized biochemical building blocks.

    In the manufacturing hall, workers see pallets of clean, white-to-pale-beige crystalline flakes. Each batch undergoes strict checks—purity, melting point, moisture content—to meet consistent specifications. Our main model product comes with a minimum purity specification of 99%. That level of purity is not just for marketing; it is required for downstream reactions to avoid contamination, improve reproducibility, and make processing safer and more efficient.

    Key Properties and Performance in Application

    Chemists in various sectors reach for 2,4,6-Trichlorophenol because it combines strong chlorinating potential with the reactivity profile that chlorinated phenols offer. In one use, it acts as an intermediate for the synthesis of herbicides, especially those seeking selective weed control without lingering residues. As a microbicide raw material, its effectiveness comes from the multiple chlorines providing a broad antimicrobial spectrum. These attributes depend on a high content of the target compound, without interference from over-chlorinated or under-chlorinated byproducts.

    Due to the hydrophobic nature and aromatic structure, this compound tends to have limited solubility in water but better compatibility with common organic solvents. This characteristic makes it easier for formulators to work with it in organic reactions and for blending into systems where water causes hydrolysis or activity loss.

    Why Downstream Producers Choose Our Material

    Refiners of pharmaceuticals, pesticide manufacturers, and dyestuff companies send us their feedback week after week. Many have tried blends or lower grade material from sources that use recycled chlorination feedstock, only to find that the presence of 2,4-dichlorophenol, 2,3,6-trichlorophenol, and other side-chlorinated products causes unexpected pigment changes, off-odors, and lost yield. We focus our process on direct chlorination with close temperature control and a controlled phenol-to-chlorine ratio, so our finished product avoids common isomers that create those problems.

    From a technical operations point of view, the reduction of inorganic salt residues below 0.5% prevents fouling of downstream stirrers and jacketed kettles. A consistent particle size prevents bridging in feeders and allows for more precise control over melt-blend processes. These improvements are not accidental but the result of years sharing feedback directly with downstream users instead of traders.

    Handling and Safety Considerations

    Producers who have experience with halogenated organics know that worker safety deserves the same focus as product purity. Fume extraction and respiratory protection devices stand ready in production lines. Our process team works continuously to reduce worker contact with raw and intermediate streams, relying on automated dosing and closed transfer systems instead of open-batch handling. Maintenance supervisors stress the importance of rapid response if accidental contact occurs. Although 2,4,6-Trichlorophenol shows lower volatility at room temperature, it still requires full protective gear in production zones.

    Over many years, we have learned to preempt emissions through technology upgrades and strict process discipline. By investing in scrubber towers and batch condensers, our plant prevents fugitive chlorinated byproduct release, which aligns with both local regulations and international conventions. Wastewater from washdown and filtration gets treated using activated carbon and alkaline neutralization, allowing us to further reduce environmental impact, which remains an important part of our license to operate.

    Specification and Batch Quality Control

    Consistency matters more than just matching a specification sheet. In our lab, every shipment faces tests for purity using gas chromatography. Color and clarity checks happen side-by-side with moisture assessment, as trace water can catalyze side reactions in polymers and pesticides. We adopted a water content control standard below 0.2% to minimize such risks. Most customers focus on the melting range between 68 and 70 degrees Celsius to make sure the material will melt and incorporate evenly in their vessels without coking or premature reaction.

    Physical properties show up not only in handling but also in process safety. Our in-house technical department reviews each lot for dustiness, flow rate in gravity hoppers, and the presence of fines, since these factors influence not just automatic dosing but also safety, as powders with more fines are more likely to cause inhalation risk during transfer.

    Making the Right Choice: Why 2,4,6-Trichlorophenol Stands Out

    As direct manufacturers, we see that purity isn’t just an abstract metric but a way to reduce complaints and error risk downstream. Over the years, we watched companies try to substitute other trichlorophenol isomers—2,4,5-trichlorophenol or 2,3,4-trichlorophenol—using less controlled processes to cut cost. In doing so, they faced headaches like different reactivity profiles or the introduction of persistent off-odors caused by certain isomers that carry over from raw materials to the final formulation.

    2,4,6-Trichlorophenol’s unique blocking pattern on the phenol ring makes it less prone to Diels-Alder reactions and aromatic substitution at the open ring positions. This stability means better performance in long-lived applications such as wood preservation, where the compound’s resistance to further oxidation leads to less degradation. Engineers working in wood preservative plants comment that switching to high-purity 2,4,6 cuts down on muddy residue in treating vats. This practical difference translates into less downtime for cleaning and a smoother workflow.

    In dye manufacture, small amounts of impurities can ruin a ton of product. Because we run our lines with full traceability, our customers get the same quality, year after year, for critical color-forming steps. Soap and detergent formulators also appreciate our consistent particle size, which avoids agglomerate formation in blending tanks. Each of these details shows that the right grade of material supports both safety and efficiency in industrial-scale production.

    Market Changes and Regulatory Influence

    Like all producers of chlorinated compounds, our manufacturing must adjust as regulations shift. Over the past decade, increasing attention has turned to environmental and occupational health standards, both in our home market and globally. Several countries impose limits on the residual levels of trichlorophenols in finished goods, including textiles and paper. These restrictions stem from the compound’s persistence and potential for forming dioxins in certain closed combustion cycles.

    We addressed this issue by introducing dioxin control programs at the reactor level and verifying that batch temperatures remain within a safe range to limit the unintended formation of byproducts. Routine dioxin level checks and robust batch records back up both our claims and the confidence of downstream users whose certifications hinge on these details. This focus supports not just regulatory compliance but also the push for responsible chemistry among large purchasers and global brands.

    Operational Challenges and Solutions in Production

    Running chlorination plants brings challenges, from effluent management to storage safety. Experience taught us that process bottlenecks most often happen at the filtration and crystallization stages. Crystallizer fouling due to impurities changes recovery rates and can drive up cost. Extended holding time in mother liquors raises impurity levels and product color. To combat this, plant staff work directly with R&D teams to modify filtration cycles, introducing periodic filter backwash and slurry recirculation. Every change comes with cost implications, but the improvements pay off in stable supply and reduced downtime.

    Worker training stands as another core element of our operation. Before newcomers start, they undergo both on-the-job and classroom training with senior operators, covering everything from dealing with leaks to critical emergency shutdown steps. These are not optional measures; chemical plant safety depends on discipline and knowledge at every level. By investing in people as much as equipment, we see fewer accidents and less product lost through avoidable errors.

    Comparisons with Other Chlorophenols

    From a synthesis point of view, 2,4,6 offers a different behavior than its cousins like 2,4-dichlorophenol or 2,4,5-trichlorophenol. Customers sometimes ask if they can substitute one for another when availability or cost changes. Chemical reactivity gives the answer. For example, the para and ortho-chlorinated positions in 2,4,6 restrict additional electrophilic substitution, making the molecule less reactive toward further chlorination and preserving it in formulations where stability trumps reactivity. In contrast, more open-ring phenols, like 2,4,5, carry an inherent risk of further unwanted substitution in dye or pharmaceutical syntheses, leading to color changes or reduced yield.

    Physical handling also sets 2,4,6 apart. Its melting range supports both hot-melt and solvent-based incorporation, which processors appreciate. The difference shows up on the plant floor, where operators face less clumping and better pourability, especially in humid weather conditions.

    Not all feedstock is equal. We source our starting phenol directly from trusted partners, who provide full documentation and impurity lists. The chlorination stage includes a closed-cycle system to limit emissions and waste. This chain control affects the whole downstream path, from intermediate to finished product—something distributors rarely see but a reality for manufacturers responsible for every kilogram.

    Supply Chain Insights and Customer Relationships

    Through years dealing directly with our customers, we see what matters beyond the datasheet. Buyers want reliable delivery, responsiveness to changing order volumes, and the ability to trace every batch from raw material to finished goods. In tight markets, our plant stops less often than competitors because of better buffer storage and maintenance practices. Our logistics managers plan shipments by road and sea, using containers with interior liners to avoid cross-contamination and moisture ingress.

    Getting feedback isn’t about surveys but open dialogue. We sit with users in their factories to understand uses from wood impregnation to textile dye intermediates. Together, we’ve improved our packaging—moving from basic fiber drums to moisture-resistant multilayer bags—thanks to reports of clumping during long sea trips in tropical weather. Every adjustment starts with real-use insight instead of assumptions about what buyers might need.

    Future Directions for 2,4,6-Trichlorophenol

    No industrial product stands still. The trend toward greener chemistry pushes manufacturers like us to consider lifecycle analysis and alternate process intensification. We are exploring ways to recover heat from the exothermic chlorination stage and reuse water in non-critical wash cycles, reducing total environmental footprint. Collaborations with research institutes guide us in process optimization and new applications, such as the use of 2,4,6 derivatives in next-generation flame retardants with lower toxicity profiles.

    Many users now request documentation on the entire product journey. Full transparency on audit trails comes not from a yearly compliance rush, but from systematic record-keeping. This approach assures major buyers, especially those focused on circular economy initiatives, that their supply aligns with broader sustainability goals. Our plant engineers balance production efficiency with resource stewardship, knowing that a reputation built over decades depends on trust and a record of real solutions in tough situations.

    Operational Realities: What We See on the Shop Floor

    Walking through the plant is different from reading a product description. Every valve, pressure gauge, and storage tank tells a story of trial and improvement. Dust-free material comes from adjusting crystallizer temperature ramps and adding improved separators. Lower residual acidity doesn’t just appear; it is chased down through improved washing cycles and close monitoring of neutralization endpoints. These technical tweaks combine to shape not just the product, but the working environment—and, in turn, the ability of customers to keep their lines running smoothly.

    This inside view, gained after years of hands-on work, shapes every batch we send. Quality comes down to the details: shipment inspections, on-the-fly adjustments to drying curves, and close engagement with user feedback. Our operators know most recurring complaints start with overlooked steps in those “boring” parts of the process—rinsing filters, calibrating sensors, or checking drum seals.

    Building Lasting Value in the Chemical Supply Chain

    Holding to high production standards is a daily commitment. We know that in this market, where trace impurities or inconsistent performance cost customers both money and market share, shortcuts defeat long-term goals. Trust grows every time we solve a handling problem or troubleshoot an off-spec batch directly with a user. The reputation of 2,4,6-Trichlorophenol as a reliable chemical intermediate owes less to marketing language and more to visible reduction of batch-to-batch variability, cleaner plant environments, and hands-on technical support.

    Our technical and sales teams share a goal: improve the experience for users, not by focusing on glossy data sheets, but by giving answers rooted in daily production realities. We field questions on compatibility, solvent selection, and shelf stability, not as a distributor chasing volume, but as a manufacturer who understands both the technology and the business risks.

    Conclusion

    Our journey manufacturing and supplying 2,4,6-Trichlorophenol demonstrates that excellence in chemicals doesn’t come from the lab alone but from day-to-day reliability, practical improvements, and keeping the concerns of real-world users in sharp focus. The interplay between process stability, customer dialogue, and compliance requirements defines how we move forward and shapes the product as much as the chemical formula. By staying close to our production roots, we offer not just a compound but a manufacturing approach that values feedback, transparency, and long-term partnership.

    Top