1-Propanethiol

    • Product Name: 1-Propanethiol
    • Alias: Propyl mercaptan
    • Einecs: 203-497-4
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    264605

    Cas Number 107-03-9
    Iupac Name Propanethiol
    Molecular Formula C3H8S
    Molecular Weight 76.16 g/mol
    Appearance Colorless liquid
    Odor Strong, unpleasant, garlic-like
    Boiling Point 67 °C
    Melting Point -110 °C
    Density 0.839 g/cm3 (at 20 °C)
    Solubility In Water Insoluble
    Flash Point -18 °C (closed cup)
    Refractive Index 1.434 (at 20 °C)

    As an accredited 1-Propanethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Propanethiol is packaged in a 500 mL amber glass bottle with airtight screw cap, featuring hazard labels and safety information.
    Shipping 1-Propanethiol is shipped in tightly sealed, corrosion-resistant containers to prevent leaks due to its flammability and strong odor. It must be transported following hazardous material regulations, labeled as a flammable liquid (UN 2402), and stored in a cool, well-ventilated area away from heat, sparks, and incompatible substances.
    Storage 1-Propanethiol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as oxidizers and acids. Keep away from heat, sparks, and open flames. Store separately from food and drinking water. Use only non-sparking tools and ensure proper grounding to prevent static discharge.
    Application of 1-Propanethiol

    Applications of 1-Propanethiol in Industrial Manufacturing

    As a direct manufacturer of 1-Propanethiol, we supply this organosulfur compound to a broad range of industrial sectors, supporting specific downstream production processes that utilize its reactivity and physical properties. The following application scenarios represent real, validated industrial uses in large-scale operations along with precise technical and regulatory information required by our B2B customers.

    1. Agrochemical Synthesis: Crop Protection Intermediates

    Manufacturers in the crop protection sector use 1-Propanethiol as an alkylthiolating reagent to synthesize critical intermediates for herbicides and insecticides, particularly for selective thiol-functionalized active ingredients. It serves in nucleophilic substitution steps, introducing sulfur atoms into aromatic and aliphatic compounds that ultimately deliver target specificity in agricultural formulations. Compliance with agrochemical raw material standards, stringent process control, and final traceability for export-oriented supply chains drives specification in this segment.

    Industry compliance standards

    • REACH (Regulation (EC) No 1907/2006)
    • EPA 40 CFR Part 158 (U.S. Pesticide Registration)
    • ISO 9001:2015 for chemical synthesis quality management
    • China National Standard GB/T 19601 for pesticide intermediates

    Typical usage ratio

    • 0.5–2.5 molar equivalents, based on the specific intermediate required; adjustment follows stoichiometric requirement in thioetherification stages

    Downstream process integration

    • Direct addition to reaction vessels during nucleophilic substitution or alkylthiolation under strictly controlled anhydrous, inert conditions

    Final product types

    • Thioether-based selective herbicides
    • Aromatic and aliphatic sulfur-functionalized insecticide intermediates
    • Custom sulfur-containing pesticide molecules for contract manufacturing

    2. Odorant Formulation for Natural Gas Distribution

    Gas transmission and utility companies rely on 1-Propanethiol as a potent odorizing agent, added to natural gas and LPG to impart a detectable warning smell. The distinctive sulfurous odor enables leak detection per safety mandates for public health. Composition and dosage are determined by regulations governing minimum olfactory thresholds and compatibility with distribution infrastructure materials.

    Industry compliance standards

    • EN 13725:2022 (Olfactometry for odorant dosing)
    • 49 CFR Part 192.625 (US DOT Pipeline Safety: Odorization requirements)
    • ASTM D6273 (Odorization of Natural Gas)
    • CSA Z662 (Canada: Oil and Gas Pipeline Systems)

    Typical usage ratio

    • 1–10 ppm (parts per million) by volume in natural gas; exact rate set by required detectable limits and national regulation

    Downstream process integration

    • Metered injection into gas transmission lines at compression stations or city gate plants, using automated odorizing systems

    Final product types

    • Odorized natural gas for residential and industrial use
    • Liquefied petroleum gas (LPG) with warning odorants

    3. Pharmaceutical Intermediate in API Synthesis

    Pharmaceutical manufacturers employ 1-Propanethiol as a building block or thiolating agent during the synthesis of sulfur-containing active pharmaceutical ingredients (APIs). Its utility appears particularly in the preparation of mercaptan-containing heterocycles, modulators, and enzyme inhibitors. Compliance with pharma-grade purity standards, validated GMP production, and documentation for traceability are strictly enforced.

    Industry compliance standards

    • ICH Q7 (International GMP for Active Pharmaceutical Ingredients)
    • USP/NF monographs (for relevant intermediates)
    • EDQM CEP (Certificate of Suitability to the Monographs of the European Pharmacopoeia)
    • FDA 21 CFR 210/211 (Current Good Manufacturing Practice regulation)

    Typical usage ratio

    • 1.0–1.2 equivalents per target molecule synthesis, optimized per stepwise yield and minimizing side reactions

    Downstream process integration

    • Incorporated during heterocycle construction, sulfur-bridging, or functional group modification under nitrogen or argon atmosphere, typically within multi-step batch reactors

    Final product types

    • Sulfur-containing small-molecule drug APIs
    • Intermediates for antimicrobial agents and central nervous system drugs
    • Custom contract synthesis projects for pharma R&D

    4. Flavor and Fragrance Synthesis

    The flavor and fragrance industry incorporates 1-Propanethiol as a precursor for certain sulfury, savory, or meaty aroma compounds used in food additives and complex perfumery accords. Downstream formulators transform it via esterification or oxidation into key flavor chemicals, matching regulatory thresholds for food safety and international additive acceptance.

    Industry compliance standards

    • FCC (Food Chemicals Codex) for food ingredient identity
    • EU Regulation (EC) No 1334/2008 (Flavorings and Food Ingredients)
    • GRAS (Generally Recognized As Safe) status for approved derivatives
    • IFRA (International Fragrance Association) guidelines for perfumery

    Typical usage ratio

    • 0.01–0.05% w/w in concentrated flavor or fragrance bases; calculated to ensure sub-ppm levels in finished consumable goods based on intensity and regulatory limits

    Downstream process integration

    • Batch or continuous synthesis of thioesters, aldehydes, or mercaptans for flavor/fragrance blending; followed by distillation and blending into finished formulations

    Final product types

    • Artificial meat and savory food flavor concentrates
    • Onion, garlic, and cooked-meat flavor notes
    • Sulfur-based perfume accords for signature fragrances

    5. Rubber Vulcanization Accelerator Synthesis

    In the specialty rubber sector, 1-Propanethiol acts as a precursor for producing thiuram, dithiocarbamate, and mercaptobenzothiazole class vulcanization accelerators. These organosulfur chemicals enhance curing efficiency and final physical properties of industrial and automotive rubber products. End-users adhere to industry standards for product safety, compound stability, and environmental compliance in tire and technical goods production.

    Industry compliance standards

    • ASTM D2000 (Classification System for Rubber Products)
    • EN 14236 (Rubber accelerators and their safety)
    • ISO 9001:2015 (Quality Management System)
    • REACH (European Chemicals Regulation) for accelerator registrations

    Typical usage ratio

    • 0.3–1.0 equivalents, introduced for reaction with carbon disulfide, amines, or related intermediates; quantity set by target accelerator formulation

    Downstream process integration

    • Initiation of sulfur donor chemistry via thiolation reaction, followed by purification and compounding into powder, pellet, or liquid accelerator forms

    Final product types

    • Thiocarbamate and thiuram accelerators for tire and technical rubbers
    • Pre-dispersed sulfur additives for high-quality automotive parts
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    Certification & Compliance
    More Introduction

    Introducing 1-Propanethiol: Insights from Our Production Floor

    Real-World Application and Distinct Advantages of 1-Propanethiol

    In our years manufacturing organic raw materials for chemical industries, we have watched 1-Propanethiol (also known as n-propyl mercaptan, with CAS number 107-03-9) shape production routines and product design at a practical, hands-on level. This clear, colorless liquid belongs to the family of alkylthiols, a group recognized for their signature sulfur aroma and reactivity. The molecule, C3H8S, brings its unique properties into every application—not as an interchangeable solvent or reagent, but as a tool with a well-defined role dictated by its chemistry.

    One finds that 1-Propanethiol isn’t simply another chain-length variant of mercaptans. Every detail, from its manageable boiling point to its solubility profile, matters for the plant floor or R&D bench. In agriculture, it earns its reputation as a building block for synthesis, not just as a stench agent for gas leakage. Fuel industries use 1-Propanethiol when strict olfactory traceability is required in natural gas supply, and calibration must balance potency and volatility. Chemical synthesis operations rely on its nucleophilicity to direct specific organic transformations—especially in thioether or sulfonate construction. Many flavor and fragrance chemists try to mask its natural pungency through careful dilution, while leveraging its reactivity for complexity-building steps that broader-minded scent molecules can’t match.

    Model Variations and Practical Handling

    True differences in raw material quality sit in the details: water content, purity, and organosulfur impurity profiles. We produce 1-Propanethiol at purity levels typically at or above 99%. Our process screens out heavier sulfur analogues and halogenated leftovers, both for process reliability and to prevent equipment corrosion during downstream use. High-grade lots ship with water content below 0.1%, drastically reducing concerns about hydrolysis or unintended oxidation. Specifying grade matters in synthesis; lower purity aligns better with gas odorization uses, whereas higher purity is crucial for flavor, pharmaceutical, or sophisticated specialty chemistries.

    From day one, shipping and storage demand real attention. 1-Propanethiol is volatile, so we employ stainless steel drums or HDPE containers with proper seals. Over many shipments, we have found that minimizing ambient oxygen stops product darkening and controls peroxide buildup. Direct sunlight triggers degradation far faster than most first assume. Good labeling is not just regulatory: its distinct aroma carries risk if storage isn’t separated from oxidants or alkalis, and spills command immediate response, not only because of odor, but also potential fire risk. Our teams treat this as a matter of daily discipline, not an afterthought.

    Why Customers Choose 1-Propanethiol Over Alternatives

    Selection isn’t merely a matter of sulfur count or chain extension. Comparing 1-Propanethiol with its most common relatives—methanethiol, ethanethiol, or heavier butanethiols—distinctions grow stark. Methanethiol’s low boiling point poses venting challenges, especially in warm settings. Ethanethiol, a common gasoline odorant, is far more persistent but trickier to control in flavor work. By contrast, 1-Propanethiol offers a middle road: strong enough for gas traceability, volatile enough for clean removal after reaction, but not so tenacious as to contaminate final blends. Its molecular structure gives reactions more predictability; longer or branched thiols show sluggish nucleophilicity or produce too much steric hindrance, leading chemists back to 1-Propanethiol for fine-tuned synthesis.

    Odor alone rarely seals the decision. While some customers request thinner, less pungent mercaptans, most find 1-Propanethiol easier to scrub from final matrices than higher homologues. For traceability in hydrocarbons, technicians appreciate the balanced profile; boil-off points align well with LPG or natural gas behavior, guaranteeing odor detection at low ppm without trapping residue in downstream piping. From our field visits, both maintenance teams and plant operators comment that tank cleaning time drops when 1-Propanethiol runs as the marker, compared with heavier analogues.

    Role in Industrial Synthesis and Research

    As a manufacturer, we develop 1-Propanethiol to meet rigorous standards in pharmaceutical and specialty chemical synthesis. Researchers want homogenous lots, free of sulfur contaminants that cloud analytical results. In pesticide manufacturing, we see demand for consistently high-purity thiols—grainy, off-spec batches stall entire reactors. Lab chemists rely on assured reactivity in cross-coupling, acylation, and methylation chemistry; batch to batch consistency matters more than theoretical yield.

    On the research side, experienced users notice differences in reactivity depending on minor impurities: excess water drags down yields, and oxidative discoloration complicates post-reaction isolation. We invest in inert-atmosphere production setups to suppress side reactions. On our line, operators constantly monitor raw feedstock quality and run inline GC analyses for every lot, which lets us catch drift in purity and intervene early. Some customer requests even specify maximum levels of trace oxygen, indicating the degree of sensitivity in certain syntheses.

    Process safety underlies every stage. We have built decades of in-house knowledge about pressure venting, emergency shutdowns, and handling minor leaks without product loss. Thiols attract scrutiny from auditors and EHS officers given their pungent emissions and potential for flash fire in confined systems. Employee training and robust PPE protocols shape our practices—avenues no datasheet or TDS can fully capture. Maintaining open channels with users ensures these lessons feed directly back to product design and shipping methods.

    Practical Use, Safety, and Environmental Responsibility

    One consistent thread across industries is the need for tight process control. 1-Propanethiol shouldn’t circulate without a clear handling plan. Seasoned site managers ask for full batch provenance and storage guidance, including monitoring for peroxide formation, as sulfur volatiles interact with air over time. Routine monitoring—using methods such as GC-FID or colorimetric tubes—informs both process safety and post-use remediation. Disposal doesn’t end at shipment; we prepare handling guides for incineration or chemical scrubbing, matching disposal technology to local regulation and waste management capabilities.

    The environmental footprint forms part of our operational ethos. Stringent control during synthesis helps limit volatile organic compound releases, but the true impact shows in downstream use. End-of-life considerations prompt us to guide customers toward integrated scrubbing and recovery systems—minimizing both plant risk and urban impact. Working with municipal authorities over the years has given us a sense of the real challenges: odor complaints shift policy and licensing faster than chemical registrations ever will.

    Industry-wide, few chemicals create a swifter complaint than sulfur volatiles. Our process teams proactively update fume extraction and abatement; in process upsets, local meters give instant alarms mapped to individual compounding lines. This hands-on approach to emission response keeps us in good standing with neighboring communities and local regulators. We’ve found that transparency goes further than compliance—reporting near misses is the only way to build shared trust and update internal protocols to fit real-world conditions.

    Quality as an Ongoing Commitment

    For every batch leaving our gates, technicians confirm composition and certify origin. Many users conduct double-check analyses, not from distrust but because synthesis with volatile sulfur species demands it. Failures in odorant traceability or key intermediate synthesis cost more than any margin saved from sourcing off-grade. Our own continuous feedback loop—production samples analyzed at multiple points, rapid communication with end users, and investment in staff training—keeps quality loss from creeping into operation.

    Requests change year by year. Five years ago, most buyers took standard drummed product; now, many request nitrogen-blanketed small packs for in-plant use or pre-measured ampoules for analytical calibration. We adapt by upgrading packaging lines and retraining staff, the kind of changes that stay invisible to the untrained eye but mean the difference between quality control success and scrap generation for advanced manufacturing clients. Our logistics teams work days ahead to match international shipment restrictions, watching for new hazardous material laws and consulting with freight partners before paperwork is ever filed.

    Beyond the Product: Manufacturing Experience Shapes Reliability

    Our own experience puts front-line knowledge ahead of any paper specification. Batch-to-batch management is built on noticing subtle differences—a shift in odor profile, a tinted liquid surface, or a low-yield batch from off-spec raw material. Troubleshooting starts with open lines between production and technical support. Watching raw material performance in the field slightly off specification informs tweaks in processing that no global standard can mandate. When environmental limits tighten or analytical standards sharpen, we realign purification routines and update drums and valves to guarantee containment.

    We run internal pilot tests for every process shift, using small-scale reactors to simulate new customer requests before moving to full capacity production. This avoids surprises at scale; real incidents, like a drum rupture due to mislabeled fill weights or a valve jam from hastily-repaired gaskets, taught us that preventive measures outpace any regulatory checklist. Thousands of liters in inventory add risk, so we source hardware from vetted suppliers, and maintain traceability for every ton. Problems solved in one campaign often resurface years later in a new configuration, so documentation and “lessons learned” databases cut repeat mistakes.

    Career Insights: Producing 1-Propanethiol with Accountability

    Manufacturing 1-Propanethiol is as much about building relationships as it is about process chemistry. Years in production teach that buyers remember quick, transparent support—especially when an off-odor or purity dip threatens a shipping deadline. Our supply chain hinges on being honest about unexpected variations or batch adjustments, and collaborating with customers to solve problems in real time. Many clients have strict regulatory checklists for thiol content, so transparent documentation and pre-shipment quality files keep projects moving. Site visits reveal bottlenecks overlooked in remote negotiations: a missing vent hood or blocked drain alters safe handling, and shared solutions carry the day.

    We often field questions around shipment tracking or customs, but the real challenge lies in adapting product format and certification to regulatory shifts. In the past, shifting from UN-approved metal drums to HDPE packaging required multiple reruns of drop tests, and close communication with shippers. True value shows in smooth handoffs, clear paperwork, and availability for troubleshooting—practices that software or data sheets never stand in for. Our best learnings come from on-site troubleshooting in client facilities. No handbook captures the nuances of caring for thiol inventory through a multi-shipment journey.

    Grounded Perspective: The 1-Propanethiol Standard

    1-Propanethiol stands out not through generic claims, but through precise, consistent performance established by real manufacturing experience. From selecting reactor materials (favoring corrosion-resistant alloys), to vetting drum closures, to refining reactant feeds in pursuit of stable product output, every step demands active involvement. Regular audits by third parties and internal teams back up our documentation. This isn’t bureaucracy: live feedback on reactivity, odor release, and storage stability allows us to surpass baseline compliance—truly serving both client and regulatory interests.

    We see value in continuous improvement, whether it’s refining purification steps to further reduce trace sulfur contaminants, adding monitoring for emerging odorant regulations, or collaborating with logistics teams to expedite hazardous shipments worldwide. As raw material purity standards increase market-wide, our systems flex to raise performance thresholds without sacrificing process safety. Fielding feedback from real users, acting on near-misses, and sharing honest assessments makes up the foundation for responsible production of 1-Propanethiol.

    Conclusion: Our Legacy and Mission with 1-Propanethiol

    The most valuable lessons in chemical manufacturing come not from product marketing, but from listening to the needs of actual users, understanding their day-to-day pressures, and delivering consistent, safety-focused supply. Decades producing 1-Propanethiol have taught us that quality control, safety, and open communication are not optional extras but the main pillars of responsible manufacturing. As the world of specialty chemicals moves forward, the demands only grow stricter; we remain committed to steering our processes with experience, honesty, and direct engagement—ensuring 1-Propanethiol continues to earn its role across industries from gas odorization to specialty synthesis.

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