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HS Code |
858202 |
| Name | 1-Pentanethiol |
| Molecular Formula | C5H12S |
| Molar Mass | 104.21 g/mol |
| Cas Number | 110-66-7 |
| Appearance | Colorless to pale yellow liquid |
| Odor | Unpleasant, skunk-like odor |
| Boiling Point | 121-123 °C |
| Melting Point | -92 °C |
| Density | 0.829 g/cm³ at 20 °C |
| Refractive Index | 1.440 |
| Flash Point | 22 °C (closed cup) |
| Solubility In Water | Insoluble |
| Vapor Pressure | 18 mmHg at 25 °C |
| Pubchem Cid | 8031 |
As an accredited 1-Pentanethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1-Pentanethiol is packaged in a 100 mL amber glass bottle with a secure screw cap and a chemical hazard label. |
| Shipping | **Shipping Description for 1-Pentanethiol:** 1-Pentanethiol should be shipped in tightly sealed, chemical-resistant containers, clearly labeled and stored upright. This flammable liquid requires cool, well-ventilated transport away from heat, sparks, and incompatible substances. Comply with DOT regulations, including appropriate hazard classification and labeling. Personal protective equipment is recommended for handling during transit. |
| Storage | 1-Pentanethiol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat, and sources of ignition. Keep it away from oxidizing agents, acids, and bases. Ensure containers are properly labeled and compatible with thiols to prevent corrosion or leaks. Store under an inert atmosphere if prolonged storage is required. |
Applications of 1-Pentanethiol in Industrial ManufacturingWith a strong track record in specialty chemical production, we supply 1-Pentanethiol for distinct industrial segments requiring precise control over sulfur introduction, modification of organometallic structures, and fine-tuning of final product characteristics. Below we highlight proven downstream applications, with detailed requirements for compliance, dosage, production integration, and end-use profiles. 1. Specialty Lubricant Additive SynthesisIn the specialty lubricant sector, formulators use 1-Pentanethiol to introduce nucleophilic sulfur into alkylated additive intermediates, facilitating the production of thioester- and mercaptan-functionalized molecules that improve extreme pressure (EP) and anti-wear performance in demanding mechanical environments. The thiol group modulates molecular polarity, enhancing film strength on metal surfaces and stabilizing lubricant properties under fluctuating load conditions. This application demands consistent thiol purity and precise dose management to avoid adverse reactivity during downstream antioxidant or detergent addition Industry compliance standards
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2. Agrochemical Intermediate ProductionManufacturers in the crop protection industry select 1-Pentanethiol as a building block for synthesizing sulfur-containing intermediates, especially for dithiocarbamate and thiol-functionalized pesticide actives and safeners. It acts as an important alkylation agent, delivering C5-side chains in molecules that modulate volatility, soil sorption, and controlled breakdown in the field. Rigorous process controls regulate the introduction of this thiol to balance reactivity with generation of byproducts during solvent extraction and downstream crystallization. Industry compliance standards
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3. Polymer and Rubber Vulcanization ModifiersTechnical teams in the polymer and rubber industries employ 1-Pentanethiol as a vulcanization modifier, specifically for customizing the cross-linking density and flexibility of synthetic elastomers. It enables control over network uniformity and chain mobility in elastomer systems such as styrene-butadiene and nitrile rubbers. The thiol functionality interacts with peroxides or sulfur donors to moderate cure rates and tune resistance properties, especially in formulations targeting specialty seals or hoses. Dosing consistency is critical to ensure downstream extrusion and molding yield predictable performance metrics. Industry compliance standards
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4. Flotation Agent in Mining and Mineral ProcessingOperators in sulfide mineral processing utilize 1-Pentanethiol as a selective flotation collector to enhance separation of non-ferrous metals (such as galena or sphalerite) from gangue material. The thiol’s chemical structure enables efficient chemisorption on mineral surfaces, driving differentiation during aerated flotation. Proper dosing and process timing restrict carryover and secondary contamination. Quality assurance checks target residual collector levels in downstream effluent and concentrate streams. Industry compliance standards
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5. Organic Synthesis of Pharmaceutical IntermediatesIn the pharmaceutical supply chain, process chemists select 1-Pentanethiol as an organosulfur source for small-molecule active pharmaceutical ingredient (API) intermediates and key impurities reference standards. It participates in stepwise S-alkylation, thioetherification, and heterocycle formation in medicinal chemistry-driven syntheses. Precise addition protects stereochemical integrity, while strict controls and documentation manage trace-level residues and batch reproducibility. GMP-clean and validated production lines ensure that no external contamination is introduced at this sensitive stage. Industry compliance standards
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6. Additive in Metal Corrosion Inhibitor FormulationsCorrosion inhibitor manufacturers leverage the thiol reactivity of 1-Pentanethiol for the protection of ferrous and non-ferrous metal surfaces, particularly in harsh or variable humidity environments. The unique alkyl chain length provides a balance between hydrophobicity and surface-active adsorption, supporting protective film development in aqueous and oil-based inhibitors. Tight formulation tolerances help control surface coverage, reduce risk of galvanic attack, and prevent negative interactions with coolant or hydraulic fluids. Industry compliance standards
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At our facility, there's a healthy respect for what chemistry can accomplish when handling the right molecules with the right mindset. Among the substantial catalog of thiols, 1-pentanethiol continues to hold ground as a go-to alkyl thiol for specialty synthesis and industrial processes looking for results measured by both purity and reliability. We've learned firsthand that each batch of 1-pentanethiol produces more than a reaction—it produces confidence in the hands of those shaping compounds for tomorrow's demands.
Many thiols can carry a similar backbone, but subtle differences in chain length, handling characteristics, and impurities often dictate success or setback in technical settings. 1-pentanethiol, with its straight five-carbon chain topped by the thiol group, steps into the ring as a versatile mid-range chain molecule. Our production line does not cut corners—sulfur content, purity standards, and color retention don’t just happen by chance. 1-pentanethiol must meet specifications forged through routine QA checks and experienced eyes, not just standard paperwork.
Our product typically maintains a GC purity above 99%, running clear and nearly colorless in appearance. We push for low water and low acid content, since these factors matter when small side reactions could spell failure during a multi-step catalyst sequence or flavor synthesis. Each unit represents controlled distillation and careful atmospheric management, which our crew has refined over years of batched experience. By keeping free mercaptan odors to a minimum, we help operators run a less stressful facility, even when working with thiols notorious for strong smells.
From a practical standpoint in the lab, the carbon chain length of a thiol has dramatic impact on reactivity and application. On the short end, compounds like ethanethiol or propanethiol display high volatility and often get used for leak detection or as intermediates where strong odor is desired. The longer chains such as octanethiol and dodecanethiol slide into surfactant applications or as capping agents for nanoparticle synthesis, where bulk and hydrophobicity matter more than volatility.
1-Pentanethiol sits in the sweet spot—not too volatile, not too bulky. This particular chain provides a blend of manageable vapor pressure, which improves safety indoors, and sufficient reactivity for thiol-ene coupling, sulfur-based protective agents, and flavor compound building. Its clear identity comes through in polymer cross-linking, rubber vulcanization accelerators, and organometallic synthesis.
We draw on a combination of continuous reactor monitoring and skilled distillation handling to guide pentanethiol from its initial intermediates toward a finished state ready for demanding customers. It’s no small feat. Small spikes in temperature or lapses in nitrogen blanketing can introduce side products like dialkyl sulfides or cause unwanted color formation. Operators who have spent years on the floor understand the rhythm of reactions and the importance of each reading off the line. The difference in taste and performance between a clean batch and a questionable one doesn’t just go into the waste drum—the lessons feed right back into the next cycle.
We tap imported raw materials, but every run starts in-house, bound by requirements mapped to the needs of established flavor companies, elastomer developers, and those exploring organic sulfur chemistry for electronics. Stringent control over atmospheric moisture, raw material ratios, and transfer protocols keep our 1-pentanethiol consistent and trustworthy. Without that, downstream partners would face problems in catalytic residue, unwanted discoloration, and fouled reactors.
Our relationship with pentanethiol doesn't stop at a drum leaving the facility. We continually engage with teams on the other side of the process. The compound frequently finds itself in the trenches of tertiary organic synthesis, particularly where the sulfur atom facilitates specific cyclizations or protection strategies. Leading up to scale-up phase, flavor synthesis chemists turn to pentanethiol for its role in generating authentic savory notes or minutely controlled aroma profiles.
In polymers, pentanethiol steps in as a crosslinking agent. The moderate chain length prevents excessive plasticization while offering just enough flexibility in vulcanized networks. Elastomer developers trust its ability to produce controlled, predictable crosslinked structures, allowing downstream mixes to behave reliably under changing stress and temperature. Those who’ve spent late nights troubleshooting rolling batches of product know firsthand that subpar thiol purity means inconsistent performance in the finished material.
Organometallic researchers favor 1-pentanethiol during the creation of sulfur-metal bond models or as a ligand in nanoparticle synthesis. The five-carbon chain provides a balance: not too hydrophobic for solvents like toluene or hexane but long enough to impart stability to formed complexes and nanostructures. By maintaining strict purity, we eliminate concerns over excess thiol oxidation, which can easily throw off sensitive experiments.
Chemists accustomed to working with an array of thiols recognize early on that not all mercaptans are equal. The jump from a three-carbon chain, such as 1-propanethiol, to the five-carbon pentanethiol brings tangible shifts in boiling point, solubility, and working safety. Propanethiol boils at a significantly lower temperature and often causes headaches in storage and transfer, requiring special containment and refrigeration in large-scale scenarios.
In flavor and fragrance, pentanethiol avoids the overly sharp, gassy smell associated with low-mass thiols, instead providing a rounder, less intrusive character. For those working in oxygen-sensitive applications, the reduced volatility makes safe handling more realistic, particularly in open vessel work. While octanethiol or higher homologues offer more in terms of hydrophobic protection or bulk for surface modification, their lower reactivity compared to pentanethiol slows down transformation steps, which can stall routine batch timings.
Customers who have tested a range of thiol variants confirm that both purity and odor management set our product apart. We use customized containment and ventilation solutions in our own site, and recommend similar steps for end users who value a cleaner, more stable thiol option.
By spending years perfecting our processes, our crew knows that thiols need respect in more ways than just purity. These molecules, with sulfur attached, have a way of reminding you of their presence long after clean-up. Residual odor, tank corrosion, and airborne traces present risk both in production and at the user’s site. That’s why our drums always arrive sealed with vapor barrier liners, which shield against weathering and leaks during long-distance transport.
Maintaining constant pressure on safety and odor mitigation led us to adopt enhanced scrubbing and containment around our central tank farm. It’s common sense after dealing with early-day incidents and feedback from partners downwind. For users looking to minimize environmental complaints or regulatory fines, quality thiol product isn’t just about what’s in the drum, but how it behaves through each transfer and process step. Our team designs protocols so operators spend less time managing spills and more time focusing on core chemistry.
Part of our job as a manufacturer goes beyond just making and shipping the molecule. 1-pentanethiol, like all sulfur compounds, comes with a responsibility to the wider community. We track not only the product on its way to customers, but also every chemical we source into the process. Each drum is traceable to its batch record and raw material shipment, to ensure nothing substandard ends up in the customer’s warehouse.
Sourcing responsibly limits the presence of impurities like dialkyl disulfides or acid residues, which might not matter on paper but surface quickly in large-scale formulations. These lessons stem from years of seeing what happens elsewhere when supply chain shortcuts result in sub-par product downstream. A consistent reputation for quality saves everyone headaches—from the line operator on the factory floor to regulatory agents dropping by for inspections.
Over the years, we’ve dealt with everything from regional climate swings to unexpected shipping delays. Thiols degrade or oxidize rapidly under the wrong conditions—sunlight, moisture, or oxygen exposure all trigger processes that send off-color and off-flavor signals. Our response has always been rooted in experience: invest in vapor-tight, UV-blocking packaging and stress the importance of dry, cool storage to every account partner.
Loading and unloading drums is done with a view to minimizing air ingress. From customized seals to monitored warehouse conditions, each step reflects real problems encountered in the field. Over time, batch returns due to oxidation have dropped. Customers are no longer rolling the dice on off-specification material because they know the necessary protection runs all the way from our dock to theirs.
Feedback loops between our technical team and customer labs shape how we refine pentanethiol specifications over time. We take note when a user spots a trace impurity, slightly darker tone, or unusual reactivity shift and trace it back to the process. Refined protocols on distillation speed, raw material selection, and tank cleaning routines make the difference between average thiol and a batch that’s recognized by discerning buyers in critical segments.
Reformulation projects in the flavor industry have shown that even small changes to the sulfur content and clarity of pentanethiol affect the profile of a finished product. Fragmented communication between supplier and end user often results in misfit material. We work against that by seeking out constant feedback, building transparent specification sheets, and supporting customer pilot runs with detailed batch analysis. On the elastomer and catalyst side, the right molecule means smoother curing, more predictable batch-to-batch properties, and a lower chance of rework or complaint investigation.
Chemicals for technical or food-adjacent use face increasing scrutiny under regulations worldwide. Our quality systems revolve around routine testing—beyond simple spot tests, each batch receives GC, water, and acid evaluation. Staff are tested on protocol knowledge and equipment handling, because the best instruments mean little unless the human hands guiding them know what to look for.
In our journey so far, the value of third-party audits and voluntary certification schemes is clear. Each step, from receiving intermediates to final drum sealing, is documented and traceable. This lets end users meet regulatory and internal QA deadlines with paperwork to match. Much of the paperwork exists not just to meet minimum standards, but because experience shows that overlooked impurities, or unclear production histories, can bring entire lines to a halt under audit or user inquiry.
1-pentanethiol sits at the intersection of utility and hazard. Operators who have spent years handling its production know firsthand the importance of good ventilation, appropriate PPE, and emergency containment practices. Chemical burns, vapor exposure, or odor complaints in neighboring communities provide all the motivation needed to perfect safety routines.
We’ve put resources into air handling and runoff mitigation, limiting the impact any incident could have on the surrounding environment. Our experience has shown that odor neutralization and scrubbing, combined with operator training, reduces the risk of incident reports or regulatory backlash. Partnerships with local emergency responders keep us ready for unplanned events—a lesson learned through fire drills, leak response, and years of near-misses documented and debriefed.
Environmentally, tight process control and sealed storage reduce unintentional atmospheric releases, a key point when sulfur compound emissions come under review. Our role isn’t only to supply the product, but to lead continued improvements in how 1-pentanethiol enters, leaves, and travels through the hands of those who use it across the supply chain.
Continual improvement in how we make, store, and deliver 1-pentanethiol keeps our operation robust. Sharing best practice and industry feedback remains critical. Customers, technicians, and regulatory voices all push us toward safer handling, higher quality, and more consistent product. We bring these lessons in-house, using them to fine-tune production cycles, training, and customer advisory efforts.
As demands change across flavor, polymer, and specialty chemical development, our team listens before we scale up or revise. We’ve seen weak points in processes and addressed them before they can cost customers valuable time or revenue. Our model builds on what’s been achieved and learned, not on what looks impressive in a brochure.
Hands-on experience with 1-pentanethiol has cemented the importance of never treating any batch as just another drum in the warehouse. The compound rewards careful sourcing, focused quality monitoring, and investment in user support. From our perspective, the quality of pentanethiol affects not just immediate chemistries, but broader business outcomes across all who rely on transparent, responsible chemistry. Our approach is rooted in expertise, real-world feedback, and a commitment to driving better results for everyone handling this essential molecule.