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HS Code |
478334 |
| Iupac Name | 1-chloro-3-methylbutane |
| Molecular Formula | C5H11Cl |
| Molar Mass | 106.6 g/mol |
| Cas Number | 5402-16-2 |
| Appearance | Colorless liquid |
| Density | 0.866 g/mL at 25°C |
| Boiling Point | 91-93°C |
| Melting Point | -114°C |
| Solubility In Water | Insoluble |
| Flash Point | 10°C |
| Refractive Index | 1.412 |
| Vapor Pressure | 107 mmHg (20°C) |
As an accredited 1-Chloro-3-Methylbutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 250 mL amber glass bottle with a screw cap, labeled “1-Chloro-3-Methylbutane, flammable liquid, handle with care.” |
| Shipping | **Shipping Description for 1-Chloro-3-methylbutane:** 1-Chloro-3-methylbutane is shipped as a flammable liquid, under UN1993, Class 3, Packing Group II. It should be packed in tightly sealed containers, clearly labeled, and transported in compliance with international hazardous materials regulations, away from heat sources and incompatible substances. Adequate ventilation and spill containment measures are required during transit. |
| Storage | 1-Chloro-3-methylbutane should be stored in a cool, dry, well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Keep the container tightly closed and properly labeled. Store away from direct sunlight and moisture. Use appropriate safety containers designed for flammable chemicals, and ensure spill containment measures are in place to prevent leaks or accidental releases. |
Applications of 1-Chloro-3-Methylbutane in Industrial ManufacturingAs a dedicated manufacturer, we supply 1-Chloro-3-methylbutane to global enterprises where its chemical structure enables specific transformations in various industrial segments. Below, we outline application scenarios based on proven downstream adoption, detailed through compliance benchmarks, formulation guidance, process flows, and end-use categories. 1. Pharmaceutical Intermediate SynthesisAPI manufacturers use 1-Chloro-3-methylbutane in the synthesis of active pharmaceutical ingredients and key intermediates, especially for compounds requiring a branched alkyl halide moiety. The compound participates in nucleophilic substitution reactions, enabling precise alkylation steps critical to proprietary drug molecule development, often under strict regulatory and traceable manufacturing protocols. Industry compliance standards
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2. Agrochemical Intermediate ProductionProducers of crop protection agents and specialty pesticides employ 1-Chloro-3-methylbutane as an alkylating agent to synthesize key building blocks for selective herbicides and insecticides. Its structure permits efficient introduction of branched alkyl groups, which directly influence both the selectivity and degradation pathway of the final agchem molecule. Industry compliance standards
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3. Fragrance Intermediate ManufacturingFragrance compound blenders utilize 1-Chloro-3-methylbutane as a key intermediate in the synthesis of specialty aroma chemicals, especially esters and branched lactones. Its selective reactivity provides control over molecular structure, affecting the sensory nuances and volatility of finished aroma molecules. Industry compliance standards
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4. Specialty Rubber and Polymer ModifiersProducers of specialty elastomers and performance polymers include 1-Chloro-3-methylbutane as an intermediate for functionalization, most notably for graft modification or to initiate controlled radical polymerizations. Its incorporation enables adjustment of glass transition temperature and polymer flexibility, supporting advanced product development in the automotive and electronics sectors. Industry compliance standards
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5. Fine Chemical Alkylation for Industrial SolventsDownstream producers in solvents and specialty fine chemicals deploy 1-Chloro-3-methylbutane to introduce branched alkyl side-chains, enhancing solvency, volatility, and compatibility with target end usages. This supports synthesis of performance solvents vital for extraction, reaction media, and process cleaning in pharmaceutical, electronics, and photographic sectors. Industry compliance standards
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In the field of industrial organics, 1-Chloro-3-methylbutane—also known as isoamyl chloride—stands out among alkyl chlorides for its distinctive structure and straightforward reactivity. Our manufacturing facility has worked with this compound for decades, focusing on purity and reliable supply for a range of industries. Looking at the molecular backbone, the branching at the third carbon makes a difference in how it reacts, both in laboratory synthesis and large-scale operations. This isn’t a pantry staple for the chemical sector but a specialist’s tool, built for specific tasks where its unique action is essential.
Think about what happens during nucleophilic substitution. 1-Chloro-3-methylbutane’s primary carbon offers accessibility for attack, offering predictable performance in making esters, higher alcohols, and other derivatives. We have observed in countless batches that its boiling point—right around 90-93 degrees Celsius—gives it an edge during fractional distillation. It separates cleanly from byproducts and solvents, which supports an efficient downstream process. Even subtle improvements in distillation recovery have made a real impact on operating costs, and that only appears with consistently pure material.
From synthesis to purification, our plant’s approach to isoamyl chloride production centers on minimizing side reactions. Selectivity matters in the chlorination step, especially if you want a clean, straight product without unhelpful di- or tri-chloro contaminants. We have upgraded our batch reactors and added tighter process analytics, which has directly reduced the levels of mixed isomers and allowed tough customers in the pharmaceutical and flavor industries to meet their specifications with less fuss.
Many traders and resellers offer what looks like the same molecule, but long-term users know that isoamyl chloride can pick up trace impurities which don’t show up on a basic GC screen. These show themselves later, maybe by souring a catalyst reaction or leaving a sharp off-odor in a fragrance mixture. We run regular full-scan tests—including mass spec—to catch these offenders before filling any drums or IBCs. That’s the difference between “minimum 99.0%” and reliable performance in a customer’s process. Our in-process monitoring isn’t a marketing trick; it protects real jobs, real output, and keeps project costs predictable.
Every drum leaving our site comes with precise quality data. Our isoamyl chloride runs at a minimum 99.0% assay by gas chromatography, but usually exceeds this level—especially for long-term customers who’ve worked with our product in high-end syntheses. The water content, as measured by Karl Fischer titration, stays below 0.05%. That’s not just for show; water traces can sabotage alkylation reactions or lead to hydrolysis in storage. We also watch for acid numbers—residual hydrogen chloride can corrode storage and poison sensitive catalysts—so ours measures consistently below 0.005%.
Many smaller resellers simply blend bulk material from mixed origins and rebottle it under a generic name. We reject that shortcut. Our reputation depends on upstream transparency—customers see when their batch was made, what its analytical profile was, and what raw materials shaped its outcome. If there’s ever a doubt, our technical staff are available to discuss real production details, not just read off a data sheet.
Isoamyl chloride remains a niche specialty, but in certain fields, it earns its keep daily. Perfume houses value it as a unique alkylating agent, especially when building up ethereal, banana-like notes or tackling advanced top notes in fine fragrance. The bitterness and punch of its natural theta are hard to replicate with substitutes. Here, our customers care deeply about faint sulfur or alkene impurities, as any off-note ruins a perfumer’s blend.
In pharmaceuticals, some syntheses call for a primary alkyl chloride that gives short, controlled reaction chains. A prime example is the conversion to esters or as an intermediate for nucleoside analogues, where a high-purity starting point saves rework and raises yields. We supply several API manufacturers who have come to expect not only pure product but reliable documentation of impurity levels. This turns into real savings, as side products in intermediates can degrade product stability and force unnecessary purification steps down the line.
Academic researchers and R&D labs also use 1-Chloro-3-methylbutane as a model reactant in SN2 and elimination studies. Here, precise control and traceability from our end let scientists compare results across experiments and publications. Each ampule or drum ships with retention samples, making peer review that much easier for research consortiums aiming at reproducibility.
Some customers come to us after problems with general n-butyl chloride or sec-butyl chloride. These compounds serve in similar reactions, but their response with nucleophiles and their physical handling can differ dramatically. The methyl branch in isoamyl chloride, for one, offers a boiling point several degrees higher than n-butyl chloride, cutting losses during storage and transfer. Greater stability in air and under light further widens its uses in specialty synthesis, where staleness or yellowing can disqualify whole batches.
We have watched customers switch to our product after trials with supermarket-grade chlorides. They see better reproducibility—less chatter in batch records, fewer failed reactions, and a real bump in project confidence. Isoamyl chloride’s structure gives a slight edge in selectivity too, making it a favorite for those who prioritize clean SN2 routes with minimal rearrangement byproducts. Unlike the straight-chain analogs, this little difference can mean the survival or failure of a high-value project, especially in the pharmaceutical world where each gram counts.
Over the years, we have seen the long-term impact of proper packaging in preserving both safety and quality. Isoamyl chloride gives off strong, pungent vapors due to its robust volatility and low flash point. Fragile packaging results in loss through evaporation and complaints about handling. We ship in thick-walled HDPE containers and, for major users, stainless steel ISO tanks with full protection against UV degradation and leaks. Each drum is nitrogen-inerted, not just capped, which guards against air moisture and accidental hydrolysis. These aren’t luxuries—they are built from hard lessons learned through decades of shipping. Labs and factories can get stale or off-spec material from careless storage, especially when suppliers chase the low price at the expense of process know-how.
Our shipping department takes real-world feedback from the field. Customers report back on ease of opening, residue after emptying, and how the material holds up in various climates—from the colder northern warehouses to the sticky tropics. Those insights loop directly into container selection and filling protocol. Years ago we switched from simple screw tops to tamper-evident pressure seals after a single customer flagged vapor loss during extended storage. This detail, minor as it sounds, cut spoilage rates and improved shelf-life, especially for customers with slower drawdowns.
Manufacturing chlorinated organics calls for strict compliance with environmental regulations, not just for appearances but due to the legacy risks of chlorinated emissions and water contamination. Our facility runs a zero-discharge campaign for process water, integrating closed-loop scrubbers to recover chlorinated byproducts before they ever leave the fence. This reduces treatment costs and protects river systems that local communities rely on for drinking water and irrigation.
Waste gas is another challenge rarely discussed by resellers or smaller blenders. The volatility of 1-Chloro-3-methylbutane means it can quickly move into the air during filling or accidental spills. We run continuous air monitoring near all handling points, and our operators wear personal detectors with alarms for any spike above standard workplace thresholds. If a release does occur, containment and extraction systems click into action automatically, minimizing exposure and loss. These controls often exceed baseline compliance and were shaped by feedback from neighboring farms and towns. Maintaining trust with your literal neighbors pushes real investment in emission control.
On the downstream side, we supply networking information to users about safe disposal and recycling routes for spent containers and product residues. Our technical staff help design protocols to minimize leftover stock and promote closed-loop recovery, particularly for major customers with on-site treatment capacity. These solutions grew from honest discussions about waste—not from sales brochures or regulatory pressure but from real-world pragmatism about cost and safety.
No production line moves smoothly forever. Supply chain hiccups—above all, sourcing the right primary alcohols and chlorine—have taught us to maintain reserve stocks and cultivate trusted relationships upstream. Rather than relying on market spot buys, we run forecasts jointly with both suppliers and major clients, so unexpected spikes or disruptions hit less hard. When a flood or market shock temporarily squeezed isoamyl alcohol supply a few years ago, we warned buyers ahead of time and throttled output fairly based on historic commitments, not on price alone. No new client can buy us out of long-standing agreements, and that builds trust which eventually comes back in customer loyalty.
From a technology standpoint, we invest in better process control and waste minimization. Inline sensors, refined catalysts, and smarter purification all carry cost, but they’ve trimmed our carbon footprint by double digits over the last five years. We work with academic groups on improved methods for chlorination—aiming at lower temperature routes and better reagent recovery, lessons learned from hands-on pilot projects. It’s not theoretical; these ideas have moved from test tubes to full plant scale, changing life for operators and lowering our clients’ total impact.
Our in-house R&D keeps hunting for routes to make isoamyl chloride from greener starting points. Bio-based isoamyl alcohol is an exciting prospect, with plant-based feedstock reducing cradle-to-gate emissions. We have piloted small lots from this route, and while it's not yet possible to supply our major accounts at this scale, trials continue as raw material suppliers get up to speed. Customers looking for the lowest-carbon options can already request batches from these pilot lots. These efforts don’t show up in spreadsheets as big revenue today, but experience shows that early adoption pays off as sustainability standards tighten.
We don’t just sell a product; we back up every delivery with real-world troubleshooting. Companies have called us to walk through manufacturing snags, whether clogged valves, unexpected reaction rates, or product precipitates. Our technical staff answer from the plant floor—not an outsourced call-center—drawing on years of direct contact with the pumps, pipes, and people who keep production flowing. Each season brings new challenges: heat in the summer pushes volatility; damp autumns can sneak in water traces if seals aren’t up to snuff. By sharing field-fix tips or modifying packaging specs for local conditions, we help clients avoid waste and re-processing headaches.
Long-term partnerships matter. We regularly host collaborative audits, run joint risk assessments, and even participate directly in client process development for new syntheses. Sometimes this has meant customizing fill-sizes, altering purity cutoffs, or helping clients scale lab trials into semi-bulk production without cascading costs.
Our experience teaches that no two customers use isoamyl chloride the same way. Pharmaceutical makers, perfumers, and research centers each notice different pain points, and value different features. Listening closely, tracking usage patterns, and proactively suggesting tweaks keeps our team learning and strengthens everyone’s bottom line. Over time, the lessons from one application cross-pollinate into process improvements for others. That two-way street—manufacturer feedback and client insight—lets both sides get sharper and more resilient with every batch.
In our facility, making 1-Chloro-3-methylbutane isn’t a one-off job. It’s a commitment to consistency, traceability, and reliability. Customers rely on our technical and logistical experience—built up batch by batch, over years of hands-on work. This approach does not chase the low-cost, high-turnover trade style; it’s rooted in protecting long-term outcomes for each partner in the value chain.
For production chemists, project managers, and procurement specialists, the material inside each drum reflects far more than a CAS number or a purity figure on a spec sheet. It embodies the care, vigilance, and practical knowledge of teams who have worked to minimize surprises and resolve real-world hurdles. That’s what keeps customers returning through regulatory changes, innovations, and unexpected industry shifts.
Anyone looking to get more from each kilo of 1-Chloro-3-methylbutane—less downtime, fewer surprises, and more reliable end products—sees a difference over time. Direct-from-manufacturer experience delivers not just a product but trusted support, transparency, and readiness for tomorrow’s needs.