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HS Code |
993493 |
| Cas Number | 111-25-1 |
| Molecular Formula | C6H13Br |
| Molar Mass | 165.07 g/mol |
| Appearance | Colorless liquid |
| Density | 1.176 g/cm³ |
| Boiling Point | 155-157 °C |
| Melting Point | -87 °C |
| Flash Point | 51 °C (closed cup) |
| Refractive Index | 1.447 |
| Solubility In Water | Insoluble |
As an accredited 1-Bromohexane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging for 1-Bromohexane (100 mL) is a sealed amber glass bottle with a screw cap, featuring hazard labeling. |
| Shipping | 1-Bromohexane is shipped in tightly sealed containers to prevent leakage and contamination. It should be stored and transported in cool, well-ventilated areas, away from heat, open flames, and incompatible materials. Proper hazard labels and documentation, in accordance with DOT and international regulations, are required due to its flammable and irritant properties. |
| Storage | 1-Bromohexane should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Protect it from light and moisture. Ensure that the storage area is equipped to handle flammable liquids, and containers are properly labeled. Follow all local regulations and safety guidelines for hazardous chemicals. |
Applications of 1-Bromohexane in Industrial Manufacturing1-Bromohexane serves as a specialized alkylating agent in multiple chemical manufacturing sectors. As an experienced producer, we support global industry partners in advanced processes where purity, traceability, and functional consistency are critical throughout scale-up and continuous production. 1. Pharmaceutical Intermediate SynthesisPharmaceutical process R&D teams utilize 1-Bromohexane to introduce controlled hexyl chains into target scaffolds during the synthesis of active pharmaceutical ingredients (APIs) and building blocks for biologically active compounds. The raw material enters O-alkylation or N-alkylation reaction steps, where precise stoichiometric ratios and phase transfer conditions are validated under GMP-controlled settings. This compound supports scalable and quality-driven drug substance manufacturing with critical attention to impurity control and regulatory filings. Industry compliance standards
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2. Agrochemical SynthesisProcess engineers in the agrochemical sector employ 1-Bromohexane as a source of C6 alkyl chains during syntheses of specialty herbicide and fungicide intermediates. The material participates in nucleophilic substitution reactions yielding alkylated phenol derivatives or heterocyclic compounds. Adherence to international standards for impurity profiles and traceability governs end-use in crop protection actives, supporting scale-up from lab to pilot and full-scale reactors under strict environmental management. Industry compliance standards
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3. Surfactant ManufacturingProducers of specialty surfactants deploy 1-Bromohexane in the synthesis of cationic and nonionic surfactants where the introduction of a straight-chain hexyl group enhances hydrophobic-lipophilic balance. Following controlled nucleophilic substitution with tertiary amines or alcohols, the resulting intermediates undergo further functionalization, such as quaternization or ethoxylation, to achieve targeted surface activity and performance profiles demanded by formulators for use in detergents, emulsifiers, and dispersants. Industry compliance standards
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4. Organic Synthesis as Alkylating AgentFine chemical and materials manufacturers rely on the alkyl halide for selective hexylation during the synthesis of high-value organic intermediates, including liquid crystals and functional additives. 1-Bromohexane serves as a crucial building block in classical and modern synthetic routes where strict control over regioselectivity and conversion efficiency is vital. Its reactivity supports both batch and continuous synthesis, often under inert conditions using phase transfer catalysis or advanced coupling protocols. Industry compliance standards
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5. Flavors and Fragrance Intermediate PreparationSpecialized aroma chemical producers incorporate 1-Bromohexane for the synthesis of hexyl-substituted esters and alcohols used in designer fragrance profiles and high-value flavor compounds. Through validated alkylation routes, typically involving esterification or etherification with natural or synthetic substrates, process chemists control purity and batch reproducibility to conform to international food safety and cosmetic grade requirements. Industry compliance standards
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From our plant floor, the journey of 1-Bromohexane (C6H13Br, CAS 111-25-1) begins with careful sourcing of raw materials, precision in reaction control, and vigilant purification. Chemists use it as a versatile building block. The molecule brings together a six-carbon chain with a singular bromine atom. This balance between chain length and reactivity creates a unique profile, making it worthwhile for organic synthesis. Unlike halogenated solvents or shorter chain bromides, hexyl bromide delivers a manageable volatility, predictable handling, and results that consistently support efficient downstream chemistry.
As a manufacturer, we focus on batch consistency and crystallization avoidance—two points often overlooked in the discussion around alkyl bromides. A poorly managed process can leave behind organics that interfere with alkylation reactions. In our plant, we track impurities well below the threshold found in many laboratory samples. Frequent checks of acidity, color, and specific gravity control product flow from halogenation all the way to final packaging. Customers report fewer post-synthesis purifications and smoother product handling, echoing the work our QC teams put in.
Organic synthesis routes often call for haloalkanes that bring more than just reactivity—they need to be predictable in alkylation, offer a range of solvent compatibility, and avoid bringing in unwanted side products. In nucleophilic substitution reactions, 1-Bromohexane acts as a reliable electrophile, offering good leaving group ability due to the bromine, while avoiding the excessive reactivity and environmental issues seen with alkyl iodides. Its moderate chain allows for solvent tuning and predictable product isolation. In surfactant manufacture, the longer chain structure balances hydrophobicity, giving it a valuable place in specialty surface-active agents.
Hexyl bromide draws a distinct line compared to shorter chain bromides like 1-bromopropane or 1-bromobutane. The volatility differences alone reshape how operators handle the substance, especially in larger scale reactions. Shorter chains tend to be more volatile and can evaporate faster, raising workplace exposure risks and complicating distillation. Longer chains, such as octyl or decyl bromide, drift toward higher melting points and become less convenient in liquid-phase synthesis and storage. Too long a chain, and the reactivity can drop, while purification becomes cumbersome. In our experience, 1-Bromohexane bridges the gap—liquid at room temperature, it pours cleanly and keeps a manageable boiling range. This quality smooths out process steps, from transfer to reactor heating cycles.
Every chemical batch exiting our factory reflects technical feedback from our clients—chemist to chemist, not just producer to customer. We formulate 1-Bromohexane with different application contexts in mind. For custom synthesis houses chasing new molecular scaffolds or pharmaceutical intermediates, minimal isomer presence and tight GC purity are regular concerns. Agrochemical innovators prefer material that delivers to spec in bulk, without contamination from side-chain isomers or halogen exchange artifacts. Our process allows us to dial in physical properties to target a standard purity, most frequently 98% or greater, while keeping moisture and acid content low. This direct-from-manufacturer attention saves researchers hours that would otherwise go into re-purification or troubleshooting batch inconsistencies.
Responsibility in manufacture ties directly to user safety. 1-Bromohexane avoids the acute toxicity and environmental legacy attached to some historic brominated compounds, but its handling does require more than basic precautions. We design packaging (glass or metal drums, fluoropolymer-lined containers) to avoid reactions with the chemical’s own bromide moiety, which can leach impurities from inadequately lined vessels. The smell—unmistakable, heavy, a reminder of its class—alerts operators in the plant to leaks or process upset, and doubles as an informal safeguard. We share storage and spill protocols based on real-world incidents, not just regulatory texts, because nothing replaces the lessons of an operator who’s cleaned up a drum or mitigated a spill. Frequent air and wipe monitoring in our plant has kept operator exposures well within regulatory limits year after year.
Our clients’ projects range across fields. In small molecule organic synthesis, 1-Bromohexane sits where substitutions, additions, and chain extensions are required. In Grignard and organometallic chemistry, the material often acts as a precursor for n-hexyl magnesium reagents—a standpoint that rewards dryness and high halide content, or else yields suffer and troubleshooting starts. Lab-scale scaleups sometimes reveal subtleties: storage temperature matters, as does the ambient humidity in transfer lines. We’ve had calls from researchers where water ingress complicated aminations, and those learning curves now inform our standard shipping box designs, which add extra desiccant where customer climate demands it.
Process engineers in surfactant plants use 1-Bromohexane to build intermediate alkyl chains in the creation of ethoxylated or sulfated products. The efficacy of these target molecules stems in no small part from the reactivity and purity of the starting haloalkane. Distributors sometimes underestimate the knock-on effects of trace impurities—an outcome that has sent clients back to our lot-specified drums after troublesome offshore batches. For us, the story repeats: subpar source material means compromised yield, more workup, and costlier waste disposal.
One recurring inquiry: can end users blend, dilute, or re-distill our product before use? The short answer rests in consistency: our batches run clean enough that direct use remains typical, but we always recommend trial sampling over full-scale commitment for new projects. Our support draws on the ordinary experience—gas bubbling observed during shipments (from pressure changes)—so we advise letting containers acclimate to plant temperature before unsealing.
Over the years, we’ve watched global procurement shift. Smaller buyer-lab networks look for local intermediates to lessen customs hurdles and reduce shipping risks. A decade ago, most specialty 1-Bromohexane orders targeted research divisions and small-batch pharmaceuticals. Now, surfactants, flavors, and even specialty polymer additives account for a greater share, with buyers paying close attention to provenance, trace metal content, and chain isomer ratio. Our pilot reactors run parallel trials to supply both, learning from the up-and-downs of both high-value and price-sensitive markets.
Sustainability pressures now demand that we account for waste bromide and process effluents, so process engineers keep refining our halogen recovery step. What ends up in the drum always reflects leftover challenges in the factory: incomplete reactions cost us more in both lost product and clean-up. Reliable yields result from careful control, and our track record stands up to customer audits thanks to this focus.
It is easy for those outside the manufacturing loop to become focused on a single number—GC purity, for example. Actual use tells a fuller story. Off-odors, subtle yellowing, dryness, even minute polymerization can impact downstream chemistry. Our materials science team spends as much time testing batches for byproduct fingerprints as they do tweaking distillation curves. Tiny changes in raw material feedstock can ripple into yields or overall ease of use for a synthetic chemist.
Feedback from high-volume users has improved our shipping logs: batch-traceable barcodes, sealed sample splits, and clear documentation on handling storage changes. We test for common contaminants—not just process byproducts, but drum-seal leachates and atmospheric moisture pickup. These details matter when a 500-liter reaction depends on nothing more than predictable chemistry.
We work under oversight from both national chemical registry systems and international transport safety protocols. Every batch aligns with shipping standards for hazardous goods, an area where even a minor oversight could cause customs seizures or lost shipment. Our compliance isn’t just paperwork—it’s about avoiding real disruption to a customer’s process flow. We invest in training, signage, and storage upgrades not out of obligation, but because a single accident can undo years of customer trust. Recent regulatory emphasis toward full traceability and lifecycle transparency simply reinforces habits well-engrained in experienced manufacturers.
Bulk chemistry buyers appreciate clear answers about what makes source material different. Our factory’s location, process transparency, and established supply record distinguish direct-from-plant batches from outsourced or relabeled imports. Downtime due to contamination or supply chain breaks underscores these advantages—chemists prefer knowing where the bottle comes from, having access to batch support, and seeing proof of storage conditions before arrival.
Directly supplied 1-Bromohexane saves lead time on documentation requests, and the tighter feedback loop speeds up troubleshooting when something goes awry. Long-term partners tell us that consistent packaging and technical support minimize the friction that often comes with off-brand intermediates. We pride ourselves on the technical conversation—chemist to chemist, not just form-filling and shipping. Supply chain interruptions, especially notable during logistics disruptions, have made many rethink how batch provenance and technical backup matter beyond price lists.
Chemical manufacture never stands still. The landscape for 1-Bromohexane continues to shift as end users update processes or regulators introduce new benchmarks. We’ve invested in reactor improvements, solvent minimization, and energy-efficient purification steps not for publicity but because every percentage point in yield matters when daily output counts. Clients seek even tighter byproduct controls and want real-time data tracing—trends that push us to innovate in batch monitoring and documentation.
Discussions with research partners lead to new use cases, whether that means shorter supply cycles for developmental chemistry, or novel applications in emerging materials. The real differentiator remains steady: manufacturer-backed support, a quality assurance chain that stretches from the raw material dock to the drum loaded on a truck, and a technical rapport that doesn’t leave customers solving problems alone.
We stand by each batch because we know the conditions, choices, and challenges behind it. Sourcing 1-Bromohexane straight from the facility where it’s produced means no guesswork on handling standards, no surprises from relabeling, and direct access to technicians who manage process improvement in real time. Decades of knowledge reflect in small details—tight seals, batch-tested desiccants, honest shelf-life assessments, and continuous feedback on quality risks. Each story from end users feeds back into our production notes, closing the loop and raising the bar for every future shipment.
We see 1-Bromohexane as more than a commodity reagent. It’s the result of years of refinement, attention to safety, and a willingness to update methods based on field performance. Customers return for consistent supply, straightforward support, and the confidence that only comes from working directly with manufacturers who own every step from reactor start-up to shipping. This commitment sits at the core of what makes our product stand apart—and why we remain dedicated to meeting the changing needs of the chemists, engineers, and innovators who use it.