Products

1,2,3,5-Tetrachlorobenzene

    • Product Name: 1,2,3,5-Tetrachlorobenzene
    • Alias: Benzene, 1,2,3,5-tetrachloro-
    • Einecs: 215-260-2
    • Mininmum Order: 1 g
    • Factroy Site: Yudu County, Ganzhou, Jiangxi, China
    • Price Inquiry: admin@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
    • CONTACT NOW
    Specifications

    HS Code

    908616

    Cas Number 634-66-2
    Molecular Formula C6H2Cl4
    Molecular Weight 231.89 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 140-142°C
    Boiling Point 270°C (estimated)
    Density 1.66 g/cm³
    Solubility In Water Insoluble
    Synonyms 1,2,3,5-Tetrachlorobenzol; Tetrachlorobenzene
    Smiles Clc1cc(Cl)c(Cl)cc1Cl
    Ec Number 211-232-6

    As an accredited 1,2,3,5-Tetrachlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,2,3,5-Tetrachlorobenzene, 100g, is packaged in an amber glass bottle with a tightly sealed screw cap, labeled for laboratory use.
    Shipping **Shipping Description for 1,2,3,5-Tetrachlorobenzene:** Ship 1,2,3,5-Tetrachlorobenzene in tightly sealed containers, protected from moisture, heat, and direct sunlight. Ensure containers are clearly labeled and comply with relevant hazardous materials regulations (UN 2321, Class 6.1, Toxic Substances). Handle with appropriate personal protective equipment, and transport according to local, national, and international chemical transportation guidelines.
    Storage **1,2,3,5-Tetrachlorobenzene** should be stored in a tightly closed container, in a cool, dry, well-ventilated area, away from heat, sparks, and direct sunlight. Keep away from strong oxidizing agents, acids, and sources of ignition. Store at room temperature and label clearly. Ensure storage complies with local environmental, health, and safety regulations. Use secondary containment to prevent spills.
    Application of 1,2,3,5-Tetrachlorobenzene

    Applications of 1,2,3,5-Tetrachlorobenzene in Industrial Manufacturing

    1,2,3,5-Tetrachlorobenzene serves as a critical intermediate in several specialized chemical production processes. Our material integrates directly into advanced manufacturing chains where strict compliance, precise formulation, and consistent process control are required. The following detailed sections outline major documented industrial applications, focusing on real-world downstream conversions and regulatory frameworks.

    1. Agrochemical Synthesis: Herbicide and Insecticide Intermediates

    This compound functions as a core starting material for chlorinated benzene derivatives used in agrochemical synthesis. Multi-stage chlorination and subsequent nucleophilic aromatic substitution reactions convert this input into active moieties for specific herbicides and insecticides. Strict raw material traceability is maintained throughout the agrochemical supply chain due to regulatory oversight on both intermediates and final actives.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals
    • REACH Regulation (EC) No 1907/2006
    • China GB/T 22107-2008 for pesticide intermediates
    • ISO 9001:2015 for production quality management

    Typical usage ratio

    • 40–60% by weight as the initial aromatic ring source;
    • Ratio adjusted for each downstream active ingredient synthesis; factors include reaction yield, purity specifications, and process economics;
    • Residuals tightly controlled below 1% in final technical-grade pesticides.

    Downstream process integration

    • Enters as a charge in a jacketed reactor for anhydrous chlorination;
    • Azo-coupling or nitration applied to introduce further substituents;
    • Byproducts separated via fractional distillation or crystallization;
    • Intermediates forwarded to blending and formulation steps for end-use agrochemicals.

    Final product types

    • Technical-grade herbicides for weed control in cereal crops
    • Insecticide actives for locust and beetle management
    • Herbicide blend formulations for horticultural applications
    • Granular and emulsifiable concentrate (EC) pesticide products

    2. Dye Intermediate Manufacturing

    Producers of vat and azo dyes often use this tetrachlorinated benzene as a halogen-rich aromatic core for advanced aniline, phthalocyanine, and quinone molecule assembly. The key advantage is the material’s defined substitution pattern, enabling selectivity in electrophilic aromatic substitution. Stringent controls focus on residual halogenated byproducts due to toxicity legislation in various markets.

    Industry compliance standards

    • EN 71-3 limits for heavy metals in dye-stuffs
    • ZDHC MRSL concerning chlorinated intermediates
    • 21 CFR 74 Subpart C for color additives (where applicable)
    • Oeko-Tex Standard 100 for textile dye residues

    Typical usage ratio

    • 10–30% of total initial aromatic input;
    • Ratio varies by dye chemistry and desired color strength;
    • Adjusted according to process yield and required pigment purity.

    Downstream process integration

    • Fed into high-temperature reactors for sulfonation, nitration, or diazotization;
    • Intermediates isolated prior to coupling with primary amines or metal phthalocyanine complexes;
    • Chromatographic purification removes color body byproducts;
    • Dye intermediates transferred to blending and micronization prior to textile application.

    Final product types

    • Reactive and vat dyes for cotton and cellulose fabrics
    • Azo dye precursors used in food colorants (subject to additional downstream purification)
    • Phthalocyanine pigments for plastics and printing inks
    • Acid dyes for wool and nylon textile finishing

    3. High-Performance Polymer Additive Production

    This chlorine-rich aromatic acts as a flame-retardant synergist and functional monomer precursor in engineering polymers such as polyetheretherketone (PEEK) and polyimides. The raw material supports high-temperature processing, delivering thermal stability and flame retardance to complex polymer matrices. Material traceability and contamination control define quality acceptance at this stage.

    Industry compliance standards

    • UL 94 flammability standards for polymers
    • IEC 60695-11-10 for flame-retardant additive assessment
    • TSCA Inventory Listing (U.S. EPA)
    • ISO 14001 for environmental management in polymer compounding

    Typical usage ratio

    • Up to 5% as additive for flame retardancy;
    • Up to 15% as an intermediate for specific polymer backbones;
    • Selected concentration based on target LOI (Limiting Oxygen Index) and mechanical property retention.

    Downstream process integration

    • Docked into twin-screw extruders for inline blending with polymer granules;
    • Pre-reacted with diamine or dianhydride monomers for condensation polymerization;
    • Thermal curing and devolatilization ensure residual monomer removal;
    • Masterbatch granulate produced for injection molding or film extrusion.

    Final product types

    • Flame-resistant wire and cable insulation compounds
    • Structural engineering plastics for automotive and aerospace
    • High-temperature electrical encapsulants
    • Polymer films for electronic device packaging

    4. Pharmaceutical Intermediate: Manufacturing of Chlorinated Phenols

    Chemical producers use this tetrachlorinated benzene as a precursor for chlorinated phenols, which are either direct active pharmaceutical ingredients or building blocks for disinfectants and antiseptics within the pharmaceutical sector. Strict GMP compliance, lot traceability, and impurity control are mandatory due to eventual integration into medicinal formulations.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for API production
    • USP/NF Monographs for chlorinated phenol derivatives
    • 21 CFR 211 for finished pharmaceuticals
    • Chinese Pharmacopoeia ChP 2020 relevant monographs

    Typical usage ratio

    • 20–40% by weight as the key aromatic nucleus source;
    • Adjustments vary depending on target API or disinfectant compound;
    • Final purified phenol content must reach over 99% specification for medicinal use.

    Downstream process integration

    • Undergoes hydroxylation (catalytic or oxidative processes) in GMP-certified reactors;
    • Intermediates purified by solvent extraction and chromatography;
    • Further derivatization includes etherification, carboxylation, or alkylation;
    • Finished compounds undergo rigorous batch release QC for pharmaceutical or clinical disinfectant use.

    Final product types

    • Antiseptic agents for hospital-grade disinfectants
    • Preservative actives in topical ointments
    • Raw material for further synthesis of parenteral APIs
    • Specialty surgical scrub solutions

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    Certification & Compliance
    More Introduction

    1,2,3,5-Tetrachlorobenzene: An Insider’s Look at the Realities of Production and Application

    Producing Chemicals with Consistency and Responsibility

    At our chemical plant, every batch of 1,2,3,5-Tetrachlorobenzene forms from years of experience and a commitment to detail. Each step, from selecting raw materials to watching the reactors, follows strict protocols. Real manufacturing means handling the touchpoints that can cause batch-to-batch swings if overlooked. Our production line, designed for halogenated aromatics, holds up under repeated cycles and produces clean crystals with high purity. Working directly on the line, I see the difference small changes in feedstock or temperature make to the coloration and melting point every day. There’s no substitute for this hands-on vigilance.

    Many outside the factory view chlorinated benzenes as simple commodities. For those of us responsible for making them, the reality is trickier. Raw chlorobenzene, pressure, timing, and the right catalysts mean the difference between optimal yield and a forest of byproducts. We stick to a refined chlorination protocol because unwanted isomers complicate downstream processing. Our batches often clock in at purities above 99%, confirmed by continual gas chromatography runs, keeping production steady and waste minimal.

    The Nature of 1,2,3,5-Tetrachlorobenzene

    You can spot 1,2,3,5-Tetrachlorobenzene by its white crystalline appearance and distinct odor. Even slight impurities show as color tinges, an obvious flag to trained eyes on the floor. The product melts around 139°C, and consistent melting behavior signals reliable product. Working here, you get a feel for the finer distinctions — like how particles clump or flow — that never show up in marketing material but matter for the next person down the supply chain.

    Chemical purity has more to do with professional pride here than anything else. Purity isn’t just a number on a certificate for us. Tiny impurities can build up where our pipes meet the reactors or during drying if airflow changes. Cleaning protocols, filtration schedules, and even the regularity of checks by floor operators all prevent slip-ups.

    Practical Utility: Beyond the Raw Numbers

    Most of our customers transform chlorinated benzenes into advanced chemicals: herbicide intermediates, electronic materials, or specialty polymers. Some feed the product into high-efficiency incinerators or use it in research as a standard. Talking to customers who use our material, quality matters most when their own procedures leave zero margin for error. A slightly off-melting contaminant can skew downstream reactions or poison a catalyst, costing them time and money. At our site, we have learned to tune particle size to help some partners optimize their dissolving and mixing processes. In specialty applications, they want fewer fines to avoid dust and loss.

    I’ve seen cases where an off-spec shipment forced customers to halt entire lines while waiting for corrective shipments. The responsibility weighs on us as actual producers. Trading companies often lack firsthand knowledge of these challenges, but standing shoulder-to-shoulder with production, logistics, and lab analysts teaches the difference between theoretical quality and the lived reality.

    Working with 1,2,3,5-Tetrachlorobenzene: Day-to-Day Challenges

    As a halogenated aromatic, 1,2,3,5-Tetrachlorobenzene plays by its own rules. The dust can cause skin irritation or respiratory discomfort if not handled carefully, something anyone who spends time at the packing stations will understand. We use enclosed transfer systems and dust extractors, and protective clothing is non-negotiable.

    We don't shy away from the environmental side, either. Chlorinated process water and vented gases need careful treatment to keep our impact down. Years ago, the industry learned that uncontrolled halogen discharge left marks on river ecosystems, so we've prioritized recovery systems and worked with local agencies to refine our waste treatment.

    Proper storage preserves quality. Exposure to sunlight or high humidity degrades the product and can introduce decomposition, a concern more evident in the height of summer. We store finished goods in sealed drums, away from UV and moisture, and monitor warehouse conditions round the clock. It’s not enough to make a clean batch—you have to keep it that way.

    Choosing 1,2,3,5-Tetrachlorobenzene Over Other Isomers

    The chlorinated benzenes family runs deep. I’ve seen many clients debate over 1,2,3,4- versus 1,2,3,5- or even 1,2,4,5- isomers based on what their reactors or processes need. Small structural changes lead to different melting ranges, solubilities, and reactivity profiles. For example, only certain isomers meet the selection criteria for agricultural chemistry intermediates. The 1,2,3,5- pattern avoids steric hindrance in follow-on syntheses, opening up routes for selective substitution that alternatives can't always handle.

    We manufacture multiple chlorobenzene isomers on site, which means line-switching and thorough cleaning. Each has unique applications: the 1,2,4,5-isomer targets specific chemical syntheses. Our familiarity with these differences, built up over years, lets us guide customers on selection and troubleshoot their process hiccups. Few traders can speak about how increased ortho substitution influences behavior during hydrogenation or in the formation of downstream biphenyls.

    The 1,2,3,4-isomer, for example, melts at a higher temperature and doesn’t always dissolve well in the same solvents. Customers who require particular handling or reactivity conditions learn fast why one isomer is better than another from their own plant trials. We’ve even helped long-term partners modify processes to work more reliably with the isomers they can source consistently.

    Safety Comes from the Source

    No process is risk-free. Chlorinated aromatics carry well-known hazards if managed loosely. High-purity 1,2,3,5-Tetrachlorobenzene exposes operators to less unreacted raw material than poorly controlled batches, mitigating both risk and odor issues. We train every new hire hands-on, not just in safety protocols, but in recognizing overlooked risks. At the packing stations, the air monitoring sensors become part of the team, with regular calibration to catch leaks early.

    Years ago, the industry saw accidents linked to poor separation and inattention during purification. On our floor, we've overhauled layouts to segregate incompatible goods, minimize manual handling, and automate filling lines. These actions sprang from listening to the people regularly exposed to the product, not top-down directives from outside auditors.

    Optimizing Traceability and Quality Assurance

    Every batch stands on detailed records, from raw material lots to reactor logs and lab results. Before one shipment leaves the facility, samples move through spectrometry and impurity profiling. This keeps us honest and arms customers with data that traces back to our actual production, not a theoretical certificate passed around between traders. QA isn’t another layer of bureaucracy; it’s the filter that keeps slip-ups from cascading through the supply chain.

    We maintain samples of every batch, all coded and stored for years. If someone asks a question after delivery, our labs can reanalyze the actual batch. This system has saved partnerships when something unexpected turns up down the road. The traceability system grew out of practical necessity—early in my career, missing batch records nearly cost us a major contract. We learned, and now our digital and handwritten logs are as thorough as the chemical analysis itself.

    Environmental Responsibility at the Source

    Manufacturing halogenated aromatics leaves an ecological footprint. What counts is how producers address it. We pull chlorinated vapors from exhaust and recover solvents, feeding some back into the process and cleaning the rest for safe disposal. Process redesigns have halved our water volumes needed for extraction, and collaboration with local authorities keeps discharge within strict limits. Every improvement takes time and investment, but we’ve learned shortcuts today lead to liabilities tomorrow.

    We saw issues in the past when even small leaks left residues, so process containment became a constant focus. Modern scrubbers on our stacks, regular floor integrity inspections, and community transparency on emissions ground our environmental position in direct action. Beyond hardware, training workers to spot a potential leak or abnormal color change keeps risk down and yields higher quality batches. Working on these frontlines, I know real responsibility rests with us, not with remote compliance officers.

    Learning from Experience: The Craft of Consistent Production

    Consistency grows out of the mundane: watching temperatures hour by hour, catching odors that signal a slip, and logging every deviation. Each operator internalizes factory rhythms, adjusting for seasonal changes in outside air or power quality shifts from the local grid. We cross-train teams to rotate through production, sampling, and maintenance. Everyone understands how small decisions cascade through quality.

    Upgrades in instrumentation—online analyzers, better moisture sensors, improved agitation—reduce error, but vigilant operators still catch things machines miss. Experience tells us when a batch is drifting, sometimes before lab numbers confirm it. Data-driven adjustments keep material steady and complaints low.

    We share production trends and challenges at shift change meetings. These open discussions have caught more than one process drift or raw material issue before shipments left the plant. Factoring in operator observations along with lab data, we've avoided sending out-of-spec product more than once. Human expertise, grown from direct involvement, holds equal weight with technical analysis.

    What Sets Manufacturer-Direct Supply Apart

    As direct producers, we don’t wait for issues to be flagged by intermediaries. Our teams see raw data, raw product, and the actual machinery. If a blend needs tuning or a process drifts, adjustments happen fast and at the source. Clients trust us not because we spin reassuring narratives, but because we solve problems with direct agency.

    Clients benefit from this access. They call with questions they can’t answer through standard documentation: why is melting point slightly off, or how to avoid caking in long-term storage. We give honest input drawn from running the plant. Plant tours, audits, and open calibration records replace marketing claims. This transparency sets real manufacturers apart from third parties and helps partners know they’re not dealing with a “blind” trader.

    Listening to Downstream Problems and Innovating Real Solutions

    Direct feedback drives our improvements. Users rely on predictable performance—narrow particle size, fast dissolution, and low off-odors. Years ago, we noticed variation in packaging led to moisture ingress and minor clumping for some customers in humid climates. Instead of sending replacement drums, we redesigned sealing and began vacuum-packing high-sensitivity shipments. End users saw improved flow and longer shelf life, and we fine-tuned our protocols based on their feedback.

    Maintaining direct channels lets us troubleshoot uncommon issues—when a customer’s reformulation project stalls or new environmental rules threaten supply continuity. Because we control the reaction conditions, we can test changes in advance and document real-world impacts, giving clients data tailored to their actual risks.

    Understanding the Broader Role in Industry Progress

    Chlorinated aromatics like 1,2,3,5-Tetrachlorobenzene sit upstream in many value chains. Any hiccup here ripples out, from laboratory research projects to full-scale industrial lines. Regulatory shifts and shifts in global trade pressure us to control raw material quality and predictability more tightly each year. We stay ahead by optimizing for raw material efficiency, refining catalyst usage, and continually lowering process emissions. Real manufacturing is a moving target, not a static process.

    Being part of this sector means constant adaptation. Regulatory agencies update safety and environmental requirements, and end users reevaluate their supply preferences. We track these trends and invest in new control systems that improve not just the purity of the product, but its traceability and environmental safety profile. Because our plant team engages directly with these changes, we contribute practically to industry development, not just from a distance.

    Conclusion: Integrity, Experience, and Relentless Focus on Application

    Producing 1,2,3,5-Tetrachlorobenzene means caring as much about downstream use as upstream chemistry. Every improvement in reactor control, quality assurance, or shipment security translates into real advantages for people who rely on our product to deliver. Our perspective as hands-on manufacturers gives suppliers and users confidence that their expectations meet expertise, not just promises.

    Our team’s pride grows from daily engagement, troubleshooting what goes wrong and sharing what goes right. The value we bring comes from laboring over the details: scrutinizing purity, minimizing waste, adapting to customer feedback, and upholding rigorous safety every shift. Supplying this compound isn't just a matter of ticking off specifications. It’s about upholding hard-won standards and building trust batch by batch, year after year.

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